si3D-Fect™ is a 3D transfection reagent specifically designed and developed for silencing gene expression in cells cultured on 3D Scaffolds. 3D matrices not only add a third dimension to the cells’ environment, they also allow creating significant differences in cellular phenotype and behavior. In this way, 3D matrices bearing complexes formed with si3D-Fect™ reagent and siRNA are colonized by cells to be transfected in a more natural environment. si3D-Fect™ reagent associated with 3D matrices allows numerous cell transfections in order to study tissue engineering, tissue regeneration, tumor invasion, neural differentiation, cellular polarization, tissue formation, colonization, and neurite growth.
- Highly efficient for gene silencing in 3D matrices
- Ideal for any 3D scaffolds (sponges, matrices, inserts)
- Dedicated to short nucleic acid sequences (siRNA, miRNA…)
- Long term gene silencing
- Universal (primary cells and cell lines)
- Serum Compatible