3D-FectIN™ is the newest 3D-Transfection Reagent specifically developed to directly transfect cells cultured in 3D hydrogels. 3D-FectIN™ is suitable for all kind of hydrogels and cells. 3D matrices not only add a third dimension to cells’ environment, they also allow creating significant differences in cellular characteristics and behaviors. Because 3D matrices are routinely used in basic research and therapeutic applications, OZ Biosciences has developed 3D-FectIN™ transfection reagent specific for hydrogel. In this way, hydrogel-based 3D matrices activated with 3D-FectIN™/DNA complexes are colonized by cells which are subsequently transfected in situ and in a more natural environment. This method allows studying angiogenesis, tube and acini formation, colonization, neurite growth, tissue engineering, tissue regeneration, tumor invasion, neural differentiation, cellular polarization, tissue formation...
- Highly efficient: cell lines and primary cells
- Specific for 3D Hydrogels
- Compatible with all types of nucleic acids
- Completely biodegradable
- Long term protein expression
- Serum Compatible