Cesium chloride , an inorganic compound, is an important source of cesium ions in a variety of applications. Its crystal structure forms a major structural type where each cesium ion is coordinated by 8 chlorine ions. Cesium chloride occurs naturally in mineral waters and as an impurity in carnallite (up to 0.002%), sylvite and kainite. Less than 20 tonnes of CsCl is produced annually worldwide, mostly from a cesium-bearing mineral pollucite.
Cesium chloride is typically used for density gradient work and for the purification of virus/phage, nucleic acids and nucleoproteins. It is used for the preparation of electrically conducting glasses, used to make solutions for the separation of RNA from DNA by density gradient centrifugation. Cesium chloride (CsCl) is commonly used in the separation of DNA and RNA. Procedures have been reported for the purification of closed circular DNA by equilibrium centrifugation in both continuous and discontinuous CsCl-ethidium bromide gradients. Subsequently, the CsCl can be removed from the DNA preparation by either dialysis or precipitation.
Grade: Reagent Grade
Purity: ≥99.0%
Key Applications: Density gradient, Purification
Application Areas: Molecular biology; Cell biology
Product Type: Inorganics
Chemical Class: Salts
Density: 3.99 g/mL(Lit.)
Boiling Point: 1303°C(Lit.)
Melting Point: 646°C(Lit.)
Refractive Index: 1.642(Lit.)
UV/Visible Absorbance: A50%/280, H2O ≤0.2(Lit.)
Presentation: White Crystalline Powder
Format: Crystalline Powder
pH: 5.5 - 6.5 (1% aq soln)
Solubility: Freely soluble in water (500 mg/mL),(50% aqueous-clear, colorless solution); soluble in ethanol, alcohol.
Storage & Handling: Store at Room Temperature (15-30°C), desiccate.