The Granulated media is cold filterable and gamma-irradiated for the microbiological validation of aseptic filling processes (Media fill test or aseptic process simulation). The media are supplied in triple-wrapped and cleanroom ready for the ultimate security of aseptic process. It is granulated which guarantees excellent solubility even in cold water. Cold filterability is achieved by extensive testing comprising raw materials, pre-production samples, in-process and end product control
Synonyms: TSB, CASO, Casein Soybean Digest Broth, Tryptic Soy Broth, Tryptone Soya Broth, SCDB
Application: The broth is suitable for media fill tests or aseptic process simulation according to the recommendations of the "FDA Aseptic Guide" in aseptic production lines. Due to the rich nutrient base, this medium is also suitable for the cultivation of even fastidious microorganisms. These liquid medium finds its application in pharmaceutical industry.
Legal Information: GRANUCULT is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes: Mode of action: The dehydrated culture medium is gamma-irradiated with 48-76 kGy. The intensity of irradiation guarantees that Bacteria, spores, viruses and mycoplasma are destroyed. It provides a higher level of security with regard to radiation-resistant microorganisms than other commercially available products.