Synonym: N,N′-Bis(3-aminopropyl)-1,4-diaminobutane, Gerontine, Musculamine, Neuridine
CAS Number 71-44-3
Linear Formula NH2(CH2)3NH(CH2)4NH(CH2)3NH2
Molecular Weight 202.34
Beilstein Registry Number 1750791
EC Number 200-754-2
MDL number MFCD00008215
PubChem Substance ID 24899550
Packaging
1, 5, 25 g in glass bottle
Biochem/physiol Actions
Mixed NMDA glutamate receptor agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).
| assay | ≥97% |
| bp | 150 °C/5 mmHg(lit.) |
| mp | 28-30(lit.) |
| storage temp. | 2-8°C |
| Gene Information | human ... GRIN2B(2904)
rat ... Grin2a(24409) |
assay ≥97% bp 150 °C/5 mmHg(lit.) mp 28-30(lit.) storage temp. 2-8°C Gene Information human ... GRIN2B(2904)
rat ... Grin2a(24409)