Synonym: 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine, AY 22989, Sirolimus
CAS Number: 53123-88-9
Empirical Formula (Hill Notation): C51H79NO13
Molecular Weight: 914.17
MDL number: MFCD00867594
PubChem Substance ID: 24899339
Biochem/physiol Actions
A macrocyclic triene antibiotic that binds to and inhibits the molecular target of rapamycin (mTOR). It forms a complex with FKBP12 that binds to and inhibits the molecular target of rapamycin (mTOR). Rapamycin is a potent immunosuppressant and has anticancer activity.
Quality Level: PREMIUM
Assay: =95% (HPLC)
Form: powder
Form: lyophilized powder
Color: off-white
Solubility: ethanol: soluble2 mM; DMSO: soluble
Storage Temp.: -20°C
Gene Information: human ... FKBP1A