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MilliporeSigma

Phenylmethanesulfonyl fluoride, >=98.5% (GC)

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Synonyms: alpha-Toluenesulfonyl fluoride; Benzylsulfonyl fluoride; PMSF; Phenylmethylsulfonyl fluoride

CAS Number: 329-98-6

Formula: C7H7FO2S

Formula Weight: 174.19

Linear Formula: C7H7FO2S

MDL No.: MFCD00007424

Purity: >=98.5% (GC)

Beilstein Registry Number: 2088311

EC Number: 206-350-2

UNSPSC Code: 12352202

Application: Inhibits serine proteases such as trypsin and chymotrypsin. Also inhibits cysteine proteases (reversible by reduced thiols) and mammalian acetylcholinesterase. Not as effective or as toxic as DFP. Effective concentration 0.1-1 mM. Half-life = 1 hr. at pH 7.5.

Application: Phenylmethanesulfonyl fluoride has been used in following applications:. cell fractionation.. used as a supplement in nuclear protein extraction.. inhibitor of cholesterol esterase (CE) and pseudocholinesterase (PCE).. used for the collection of blood prior to centrifugation to quantify plasma ANP levels.

Biochem/physiol Actions: Administration of PMSF produces analgesia unrelated to its anticholinesterase effect, and prolongs the analagesic effect of centrally administered β-endorphin.

RTECS: XT8040000

RIDADR: UN 2928 8(6.1) / PGII

WGK Germany: 3

R Codes: 25-34

S Codes: 26-36/37/39-45

IOD Codes: T

Symbol: GHS05, GHS06

Signal Word: Danger

Hazard Statements: H301-H314

Precautionary statements: P280-P301 + P310 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338

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Thomas No.
C976X56
Mfr. No.
P7626-250MG
Description
Phenylmethanesulfonyl fluoride, 250 mg, UN 2928 6.1/PG 2

list price/quantitytotal
$0.00
Thomas No.
C976X57
Mfr. No.
P7626-1G
Description
Phenylmethanesulfonyl fluoride, 1 g, UN 2928 6.1/PG 2

list price/quantitytotal
$0.00
Thomas No.
C976X58
Mfr. No.
P7626-5G
Description
Phenylmethanesulfonyl fluoride, 5 g, UN 2928 6.1/PG 2

list price/quantitytotal
$0.00
Thomas No.
C976X59
Mfr. No.
P7626-25G
Description
Phenylmethanesulfonyl fluoride, 25 g, UN 2928 6.1/PG 2

list price/quantitytotal
$0.00
Thomas No.
C976X60
Mfr. No.
P7626-100G
Description
Phenylmethanesulfonyl fluoride, 100 g, UN 2928 6.1/PG 2

list price/quantitytotal
$0.00
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