Polyvinylpyrrolidone 40,000, or better known as PVP, is a solubilizing polymer. It is an effective lubricant and protein stabilizer. PVP has been used to remove alkaloids and phenolics from plant tissue samples to improve mass spectrometry results. Polyvinylpyrrolidone is generally used at 2-4% concentration in aqueous solutions for DNA extraction (DNA/RNA kits) and protein purification. High quality PVP is an important component of Denhardt's Solution used for blocking in hybridization and Western blotting.
Application: For Research & Laboratory Use Only