Decalcification is necessary for optical microscopic examinations of hard tissue in routine histological procedures. For the decalcification of sensitive, calcium-containing tissues, such as iliac crest biopsies, OSTEOSOFT can be used. Its formulation is based on EDTA. Its pendant, OSTEOMOLL, can be used for the decalcification of hard tissue such as teeth and bone as its formulation is based on formaldehyde and acetic acid. Both solutions are color-coded, to distinguish them from each other, fixatives and solvents used in the histological laboratory. OSTEOSOFT is color-coded yellow, OSTEOMOLL is color-coded blue. Whereby OSTEOSOFT preserves the antigen structures in the tissue, thus, an IHC analysis can be performed, OSTEOMOLL will be used for tissues that are not destined for antibody analysis.Both decalcifiers can be used for clinical diagnostic purposes and in laboratory accreditation processes as they are certified and registered as IVD and CE product. OSTEOSOFT is used only once; fresh solution must be used for each tissue.
Density: 1.10 g/mL at 20 C
Legal Information: OSTEOSOFT is a registered trademark of Merck KGaA, Darmstadt, Germany