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Cayman Chemical

Leucinostatin A, 500 ug

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Product Description

Leucinostatin A is a fungal metabolite originally isolated from P. lilacinus with diverse biological activities.1 It is active against P. oryzae, B. cinera, P. chrysogenum, X. oryzae, S. cerevisiae, and C. albicans fungi and B. subtilis, S. aureus, S. lutea, and M. phlei bacteria in a disc assay.1 Leucinostatin A (0.1-1 μg/ml) reduces T cell activation induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) or an anti-CD3 antibody in a concentration-dependent manner.2 It inhibits proliferation of DU145 prostate cancer cells co-cultured with PrSC stromal cells in vitro (IC50 = 0.045 μg/ml).3

WARNING This product is not for human or veterinary use.

Technical Information

CAS Number              76600-38-9


Synonyms                   P168


Molecular Formula     C62H111N11O13


Formula Weight          1218.6


Purity                          ≥85%


Formulation                 A solid



  • DMF: soluble
  • DMSO: soluble
  • Ethanol: soluble
  • Methanol: soluble



InChi Code


InChi Key


Origin              Fungi/Paecilomyces sp.

Shipping & Storage Information

Storage                        -20°C

Shipping                      Room Temperature in continental US; may vary elsewhere

Stability                       ≥ 4 years

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Leucinostatin A, 500 ug
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