• PRODUCT AVAILABILITY: Did you know you can view a product's availability right on the product page? Simply enter the quantity you want to purchase and the current availability will appear below the item.

  • Product is restricted and can only be purchased by customers with a web profile linked to a Thomas Business Account - Click here to login or create your web profile. If you do not have a Thomas Business Account, please Contact Us and someone will respond with details on how to apply for a business account with us.

MilliporeSigma

JSH-23, >=98% (HPLC), solid

Not yet rated

NOTE: Due to special handling or shipping requirements, these products will have additional fees added during checkout. Click HERE for a description of what fees might be charged.

Synonyms: 4-methyl-N1-(3-phenylpropyl)-1,2-benzenediamine

CAS Number: 749886-87-1

Formula: C16H20N2

Formula Weight: 240.34

Linear Formula: C16H20N2

Purity: >=98% (HPLC)

Storage: -20C

UNSPSC Code: 12352200

Application: JSH-23 has been used as a nuclear factor κB (NF-κB) p65 inhibitor.

Biochem/physiol Actions: JSH-23 is an inhibitor of NF-kB nuclear translocation. It inhibits LPS and cytokine-induced nuclear translocation of the p65 subunit of NF-kB as analyzed by EMSA and western blot. The compound displays modest potency (IC50 7.1 uM in RAW 264.7), but has the unique property that it does not affect IkB degradation or recovery. The compound dose dependently inhibits LPS induced expression of cytokines, COX2 and iNOS, and presumably binds to, or interferes with the NLS of p65.

Other Notes: Light and air sensitive.

RIDADR: UN 3077 9 / PGIII

WGK Germany: 3

R Codes: 22-41-50/53

S Codes: 26-39-60-61

IOD Codes: Xn,N

Symbol: GHS05, GHS07, GHS09

Signal Word: Danger

Hazard Statements: H302-H318-H400

Precautionary statements: P273-P280-P305 + P351 + P338

Please Enter Your Order Info

Filter by:

  • Clear Filters
Product Detail
Thomas No.
C974L85
Mfr. No.
J4455-5MG
Description
JSH-23 =98% (HPLC), 5 mg, UN 3077 9 / PGIII
CAS Number
749886-87-1
list price/quantitytotal
$0.00
$0.00 (0 Items)
Product is restricted and can only be purchased by customers with a web profile linked to a Thomas Business Account - Click here to login or create your web profile. If you do not have a Thomas Business Account, please Contact Us and someone will respond with details on how to apply for a business account with us.

Write A Review