The gene HSA (human serum albumin) is mapped to human chromosome 4q13.3. The gene encodes a protein of 585 amino acids with a molecular weight of 66.4kDa. HSA is the most abundant protein in the plasma and has many metal-binding sites.
Synonyms: GIG20; GIG42; HSA; PRO0903; PRO1708; PRO2044; PRO2619; PRO2675; UNQ696/PRO1341; serum albumin
Purity: >=98% (SDS-PAGE)
Storage: 2-8C
Application: HSA (human serum albumin) has been used for the development of automated dye-binding method for serum albumin determination using bromcresol purple. It has also been used to study effect of HSA on DNA transfection by lipoplexes.
Biochem Physiol Actions: HSA (human serum albumin) mainly works as a carrier for various nutrients, metabolites and xenobiotics. It interacts with plasma zinc and regulates uptake of zinc in cells. HSA plays a crucial role in drug pharmacokinetics. It also controls oncotic pressure and volume of the blood. Mutations in the gene are linked with congenital analbuminemia and familial dysalbuminemic hyperthyroxinemia.