Histosec® pastilles (without DMSO) is an embedding medium for histology of samples of human origin. It is a paraffin enriched with polymers, also available with the addition of DMSO (dimethyl sulfoxide). DMSO increases the rate of penetration of paraffin and provides additional preservation of the tissue structures. Its melting range is between 56 - 58°C and, within this range any specimen can be processed without fear of damage irrespective of the method used.
In most clinical laboratories the paraffinization is performed with an automated embedding system and is performed directly after the histoprocessing.
The Histosec® pastilles (without DMSO) are well soluble with the Intermedia Xylene or xylene substitutes (such as Neo-Clear(R)).
The paraffin is an IVD registered product and CE certified, thus can be used for clinical diagnostic purposes.
Boiling point: >350°C
Flash point: >100°C
Melting Point: 60°C
Solubility: (20°C) practically insoluble