Synonym: Bovine hemoglobin, Hb, Methemoglobin
CAS Number: 9008-02-0
MDL Number: MFCD00131282
eCl@ss: 42030116
Application
The solubility of α-elastin has been applied to construction of elastin-mimetic biomaterials.
Caution
Since native hemoglobin is readily oxidized in air, these preparations may be predominantly methemoglobin.
Preparation Note
Prepared from washed, lysed and dialyzed erythrocytes.
Biochem/physiol Actions
Oxygen transporter. The Fe2+/Fe3+ balance is a physiological indicator of blood oxygenation; deoxygenated hemoglobin accessorizes a feedback loop by reducing nitrite to NO, a vasodilator which enhances blood flow to oxygen-deprived tissues.
General Description
Hemoglobin is the major component of red blood cells, and is responsible for their red color. Its normal concentration in erythrocytes is 34%. Hemoglobin is the most important respiratory protein of vertebrates by virtue of its ability to transport oxygen from the lungs to body tissues, and to facilitate the return transport of carbon dioxide.
Form: substrate powder
Mol. Wt.: Mr ~64500
Solubility: H2O: soluble20 mg/mL
Suitability: suitable for protease substrate
Storage Temp.: 2-8°C
Gene Information: cow ... HBA1(281221), HBB(280813), HBE2(513240), HBE4(513108), HBG(511735), alpha globin(512439)