Synonyms: Anti-ERRbeta; Anti-NR3B2
MDL No.: MFCD06798439
UNSPSC Code: 12352203
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Application: Anti-Estrogen-Related Receptor Î² antibody produced in rabbit was used for immunocytochemistry of neurons from mouse model of glaucoma at a working dilution of 1:500. It was also used for immunohistochemistry of mouse brain sections.
Biochem/physiol Actions: Estrogen-Related Receptors (ERR) are hormone receptors that bind estrogen response elements that in turn bind specific DNA sequences and regulate transcription. Three ERRs are known, alpha, beta and gamma, with highly conserved ligand and DNA binding sequences. ERRÎ² is selectively expressed in brain and is an important modulator of energy balance, food intake, neuropeptide levels and response to stress.
Immunogen: synthetic peptide corresponding to the internal domain of human estrogen-related receptor beta, conjugated to KLH. The immunizing peptide has 93% homology with the rat and mouse gene.
Physical form: Solution in phosphate buffered saline, containing 0.1% sodium azide.
RIDADR: NONH for all modes of transport
WGK Germany: 3
R Codes: 21/22
S Codes: 36/37-60
IOD Codes: Xn