Synonym(s): Amphotericin B from Streptomyces sp.; Fungizone
Formula: C47H73NO17
Formula Weight: 924.08
CAS No.: 1397-89-3
Application: Recommended for use in cell culture applications at 5.6 mg (solid)/L. It is used to study the formation of ion-permeable channels in fungal cell membranes
Components: Amphotericin B ~45%; Sodium deoxycholate ~35%; Sodium phosphate balance
Storage: 2-8°C
Packaging: Package size based on amphotericin B
Beilstein Registry Number: 78342
Biochem/physiol Actions: Polyene antifungal antibiotic from Streptomyces. Affinity for sterols, primarily ergosterols, of fungal cell membranes. Forms channels in the membranes, causing small molecules to leak out.
Antimicrobial spectrum: fungi and yeast.
Empirical Formula (Hill Notation): C10H12O2