"Amlodipine besylate, pharmaceutical secondary standard; traceable to USP and PhEur"

Synonyms: 2-[(2-Aminoethoxy)-methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5- pyridinedicarboxylic acid 3-ethyl 5-methyl ester benzene sulfonate; Norvasc

Formula: C₂₀H₂₅ClN₂O₅ · C₆H₅SO₃H

Formula Weight: 567.05

CAS No.: 111470-99-6

Storage Temperature: 2-8°C

Biochem/physiol Actions: Amlodipine is an L-type calcium channel blocker. Amlodipine belongs to a class of cardiovascular drugs, which act at the voltage gated calcium channel of the Ca_V1, or L-type, class. Amlodipine also has antihypertensive and antianginal effects. Its activity resides mainly in the (-)-isomer. Amlodipine inhibits growth of human epidermoid carcinoma A431 cells and has antireproductive effects in male rats.