Synonyms: Aprotinin from bovine lung; BPTI; Bovine pancreatic trypsin inhibitor; Trasylol; Trypsin inhibitor (basic)
Molecular Formula: C284H432N84O79S7
Molecular Weight: 6511.44
Linear Structural Formula: C284H432N84O79S7
MDL Number: MFCD00130541
Application: Aprotinin is largely used as an inhibitor of trypsin.
Biochem Physiol Actions: Aprotinin is a competitive serine protease inhibitor that forms stable complexes with and blocks the active sites of enzyme. This binding is reversible, and most aprotinin-protease complexes will dissociate at extreme pH levels >10 or<3. structurally, aprotinin is a monomeric globular protein derived from bovine lung that consists of 58 amino acids, arranged in a single polypeptide chain with three crosslinking disulfide bridges.<>3.>