The gene SAMD9 (sterile a motif domain-containing protein 9) is mapped to human chromosome 7q21.3. It is ubiquitously expressed. The protein localizes in the cytoplasm.
Synonyms: Anti-Sterile alpha motif domain-containing protein 9
Storage: -20C
Application: Anti-SAMD9 antibody produced in rabbit has been used in:
•immunohistochemistry
•western blotting
•immunoprecipitation
•immunofluorescence
Biochem Physiol Actions: SAMD9 (sterile a motif domain-containing protein 9) is an interferon (IFN)-?-responsive protein. SAMD9 suppresses proliferation and induces apoptosis in cancer cells. However, up-regulation of SAMD9 is associated with metastasis of esophageal squamous cell carcinoma. SAMD9 also participates in the formation of anti-viral granules. Mutations in SAMD9 are linked with normophosphatemic familial tumoral calcinosis, a disorder with progressive deposition of calcified masses in cutaneous and subcutaneous tissues.
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