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MilliporeSigma

Anti-PSTPIP1 antibody produced in rabbit Prestige Antibodies(R) Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

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PSTPIP1 (proline-serine-threonine phosphatase interacting protein 1) is a cytoskeleton-associated adaptor protein, which contains an F-BAR (bin-amphiphysin-Rvs) domain. It shares high homology to PSTPIP2 protein, and is composed of an N-terminal Fer-CIP4 homology (FCH) domain and a PEST-type phosphatase-binding domain in its coiled coil region. It also contains an SH3 domain in its C-terminal.

Synonyms: Anti-CD2-binding protein 1; Anti-H-PIP; Anti-PEST phosphatase-interacting protein 1; Anti-Proline-serine-threonine phosphatase-interacting protein 1

Storage: -20C

Application: All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry. The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.

Biochem Physiol Actions: PSTPIP1 (proline-serine-threonine phosphatase interacting protein 1) is associated with the inflammatory disorder called PAPA syndrome, which is characterized by pyogenic sterile arthritis, pyoderma gangrenosum, and acne, hence the name. This protein controls invasive macrophage migration and mediates the transformation from podosomes to filopodia-like protrusions. This protein forms a component of the leukocyte uropod, where it mediates endocytosis and cell migration.

Legal Information: Prestige Antibodies is a registered trademark of Sigma-Aldrich Co. LLC

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Product Detail
Thomas No.
CHM03C940
Mfr. No.
HPA010600-25UL
Description
HPA010600-25UL, Anti-PSTPIP1 antibody produced in rabbit Prestige Antibodies(R) Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

list price/quantitytotal
$0.00
Thomas No.
CHM03C941
Mfr. No.
HPA010600-100UL
Description
HPA010600-100UL, Anti-PSTPIP1 antibody produced in rabbit Prestige Antibodies(R) Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

list price/quantitytotal
$0.00
$0.00 (0 Items)
Product is restricted and can only be purchased by customers with a web profile linked to a Thomas Business Account - Click here to login or create your web profile. If you do not have a Thomas Business Account, please Contact Us and someone will respond with details on how to apply for a business account with us.

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