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MilliporeSigma

Anti-CCR4 antibody produced in rabbit Prestige Antibodies(R) Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

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CCR4 (carbon catabolite repressor protein 4 homolog), a C-C type chemokine receptor. CCR4 is precisely expressed on surfaces of cells such as T helper type 2 cells, regulatory T cells, interluekin-17-producing T-helper cells (Th17), and skin-homing memory. These cells are usually known to migrate toward the chemokines CCL17 (C-C motif chemokine 17) and CCL22 (C-C motif chemokine 20).

Synonyms: Anti-CC-CKR-4; Anti-CD194; Anti-CKR4; Anti-CMKBR4; Anti-ChemR13; Anti-chemokine (C-C motif) receptor 4; Anti-k5-5

Storage: -20C

Application: All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry. The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.

Biochem Physiol Actions: CCR4 (carbon catabolite repressor protein 4 homolog) plays an important role in immune cell trafficking. CCR4 is associated with the immunopathogenesis of hematological tumors and serves as an important biomarker in various types of cancer. CCR4 is involved in tumor growth and metastasis of many malignancies including gastric cancer. CCR4 is involved in tumor-induced immunosuppression. Mutations in CCR4 is associated with adult T cell leukaemia/lymphoma.

Legal Information: Prestige Antibodies is a registered trademark of Sigma-Aldrich Co. LLC

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Thomas No.
CHM02L678
Mfr. No.
HPA031613-25UL
Description
HPA031613-25UL, Anti-CCR4 antibody produced in rabbit Prestige Antibodies(R) Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

list price/quantitytotal
$0.00
Thomas No.
CHM02L679
Mfr. No.
HPA031613-100UL
Description
HPA031613-100UL, Anti-CCR4 antibody produced in rabbit Prestige Antibodies(R) Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

list price/quantitytotal
$0.00
$0.00 (0 Items)
Product is restricted and can only be purchased by customers with a web profile linked to a Thomas Business Account - Click here to login or create your web profile. If you do not have a Thomas Business Account, please Contact Us and someone will respond with details on how to apply for a business account with us.

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