Acetonitrile is a polar aprotic solvent, which is used as an intermediate in organic synthesis. It has a low viscosity, high elution strength and miscibility in water that make it viable in many chromatography systems. It can also be utilized in spectrophotometric and fluorimetric technques.
Synonyms: ACN; Cyanomethane; Ethyl nitrile; Methyl cyanide
Molecular Formula: C2H3N
Molecular Weight: 41.05
Linear Structural Formula: CH3CN
MDL Number: MFCD00001878
Purity: >=99.9% (GC)
Melting Point: -45 C (lit.)
Density: 0.786 g/mL at 25 C (lit.)
Refractive Index: n20/D 1.344 (lit.)
Application: Acetonitrile, an organic solvent, is used as a mobile phase/extraction solvent in the ultra-high performance liquid chromatorgraphy - tandem mass spectrometry (UHPLC-MS) analysis of pesticides in tobacco samples. It can be potentially used with a reverse-phase column to determine the concentration of diclofenac (DCF). It can also be used to determine the levels of serum imatinib and N-desmethyl imatinib.(5)
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