Rituximab (Rituxan) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the trea™ent of hematological cancers and autoimmune diseases. When Rituximab binds to CD20 on the surface of normal and malignant B cells, natural killer (NK) cells is…

NMU1 and NMU2 are two G-protein coupled receptors binding to Neuromedin U (NmU) that is a peptide which regulates peripheral functions such as smooth muscle contraction and blood pressure, and CNS functions including nociception and feeding activity. Compared to the wide distribution of NMU1 in…

Human Granulocyte Macrophage Colony Stimulating Factor (hGM-CSF), a hematopoietic growth factor, is mainly involved in granulopoiesis and monocytopoiesis. It is produced by T-cells and macrophages in response to antigens, and by endothelial cells and fibroblasts following induction of…

Programmed cell death protein 1 , also known as PD-1 and CD279 (cluster of differentiation 279) or PDCD1, is a protein that in humans is encoded by the PDCD1 gene. PD-1 is a cell surface receptor that belongs to the immunoglobulin superfamily and is expressed on T cells and pro-B cells.PD-1 binds…

Single donor specimens collected during the course of infection progression.

An internal standard for the quantification of (-)-11-nor-9-carboxy-?9-THC by GC- or LC-MS

Evaluate the performance of nucleic acid tests for determination of the presence of Adenovirus nucleic acids Formulated with purified, intact organisms Organisms are chemically modified to render them noninfectious Refrigerator stable—store between 2 and 8°C Purified protein matrix treated with…

Myelin oligodendrocyte glycoprotein (MOG) is found exclusively in the CNS, where it is localized on the surface of myelin and oligodendrocyte cytoplasmic membranes and has been implicated as an important autoantigen in multiple sclerosis (MS). This peptide induces severe chronic experimental…

eStain L1 is a highly efficient protein PAGE gel staining system, which uses Coomassie Brilliant Blue and a patented protein staining technology developed by Genscript. eStain L1 staining system integrates the traditional three steps of fixing- staining-destaining into one step and can…

Cell surface glycoprotein CD200 receptor 1 is a protein that in humans is encoded by the CD200R1 gene. This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is…

Evaluate the performance of nucleic acid tests for determination of the absence of Clostridium difficile nucleic acids Formulated with purified, intact organisms Organisms are chemically modified to render them noninfectious Refrigerator stable—store between 2 and 8°C Purified protein matrix…

Interleukin-5 (rmIL-5) ,produced by mast cells, T cells and eosinophils, is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). It can increase production and mobilization of eosinophils and CD34+ progenitors…

Interleukin-1 (IL-1) is a family of cytokines that play a central role in the regulation of immune and inflammatory responses to infections or sterile insults. IL-1a and IL-1ß are the first two members discovered in this family, which are the products of distinct genes recognizing the same cell…

Single donor specimens collected from donors prior to and continuing through disease progression.

FlashGel™ RNA Marker, 50 µg

Keratinocyte Growth Factor (KGF), also known as FGF-7 and HBGF-7, is a mitogen factor belonging to the heparin-binding growth factor family. It is expressed mainly by epithelial cells. KGF binds to fibroblast growth factor receptor 2b (FGFR2b) to form a dimeric complex and initiate downstream…

Programmed cell death protein 1, also known as PD-1 and CD279 (cluster of differentiation 279), is a protein that in humans is encoded by the PDCD1 gene. PD-1, functioning as an immune checkpoint, plays an important role in down regulating the immune system by preventing the activation of T-cells,…

GenScript SurePAGE, Bis-Tris, 10 cm x 8 cm gels are high-performance precast mini polyacrylamide gels with a special design that allows large sample loading volumes. The unique formulation of the gel and cassette design enables superior band resolution and significantly improved band evenness.…

Single donor specimens collected from donors prior to and continuing through disease progression.

The ZymoBIOMICS Gut Microbiome Standard is an accurately quantified microbial community mimicking the human gut microbiome. The challenges it presents to microbiomics profiling allows researchers to validate protocols and fine-tune them for gut microbiome research and act as a positive control for…

As a true third party control, assay drift is detected, monitored and managed, helping to ensure accurate and reliable results. This dedicated, positive run control is designed for use in monitoring the performance of molecular assays used in the detection of BK Virus..

Atezolizumab is a fully humanized, engineered monoclonal antibody of IgG1 isotype against the protein programmed cell death-ligand 1 (PD-L1). Atezolizumab blocks the interaction of PD-L1 with programmed cell death protein 1 (PD-1) and CD80 receptors (B7-1Rs). PD-L1 can be highly expressed on…

A certified reference material that is structurally similar to known phytocannabinoids; has been found as a byproduct in Cannabis processing; regulated as a Schedule I compound in the United States; provided as a DEA exempt preparation

Stem Cell Factor (SCF) is a hematopoietic growth factor that binds to the c-Kit receptor. SCF exerts its activity during the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures and has been shown to act…

4-1BB is a member of the tumor necrosis factor (TNF) receptor family. Its alternative names are tumor necrosis factor receptor superfamily member 9 (TNFRSF9), CD137 and induced by lymphocyte activation (ILA). It is currently of interest to immunologists as a co-stimulatory immune checkpoint…

Hot Start Taq DNA Polymerase is a recombinant, thermostable Taq DNA polymerase complexed with a thermolabile, neutralizing antibody that blocks the polymerase activity prior to the initial DNA denaturation step of PCR. When the temperature of the PCR reaction mix reaches 95°C during the initial…

Human Interferon gamma (hIFN-?) is amacrophage-activating factor and the lone member of Interferon type II. The active form of IFN-? is an antiparallel dimer that interacts with the receptor IFN-?R1 and sets off IFN-?/JAK/STAT pathway. IFN-? signaling does diverse biological functions primarily…

Stromal-Cell Derived Factor-1 alpha/ CXCL12 (SDF-1a) and SDF-1ß, members of the chemokine a subfamily that lack the ELR domain, were initially identified using the signal sequence trap cloning strategy from a mouse bone-marrow stromal cell line. These proteins were subsequently also cloned from a…

ZeptoMetrix external controls have demonstrated performance on a variety of molecular assays. The product has been tested with the Cepheid® GeneXpert® system and provides the expected results, however performance characteristics must be established by the end user. Formulated with…

ZeptoBlock is an immunoassay reagent formulated to block nonspecific binding sites of microwell plates to which antigen or antibody has been applied, thus minimizing interfering substances and cross-reactivity.

The adrenoceptors ADRA2C is expressed in the brain, kidney, aorta, lung, skeletal muscle, heart and spleen. ADRA2C knockout mice exhibited disrupts presynaptic inhibition of noradrenaline release at low stimulation frequencies.