Spermidine is a biogenic polyamine formed from putrescine.
- Essential in both normal and neoplastic tissue growth
- Plays an important role in the regulation of cellular proliferation and differentiation
- Forms stable compounts with nucleic acids
- Inhibits neuronal nitric oxide synthase (nNOS)
Spermidine binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity. It has a role in cell growth processes. It can be used in electroporation while transferring the DNA into the cell under the electrical impulse. It is also plant growth regulator, promoting somatic embryogenesis. Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.
Key Applications: Purification of DNA-binding proteins, Plant growth regulator, Electroporation
Application Areas: Cell Biology & Analysis
Product Type: Biochemicals
Density: 925 mg mL-1(Lit.)
Melting Point: 253 - 263°C
Refractive Index: 1.479(Lit.)
Presentation: White Powder
Solubility: Soluble in water (100 mg/mL - clear, colorless solution).
Sterilization of Solutions: Solutions should be sterile-filtered, not autoclaved.
Storage & Handling: -20°C, desiccate, store under nitrogen