Type: Anionic detergent
Full Name: Sodium Dodecyl Sulfate
Molecular Formula: C
12H
25NaO
4S
Molecular Weight: 288.38
Form: White to off white powder
Purity: >99%
Solubility: Water
Critical micelle concentration (CMC): 7-10mM (25°C)
Aggregation number: 62
Cloud point: >100°C
Average micellar weight: 18,000 SDS is also available as a 10% Solution or a 20% Solution
Applications
- An anionic detergent capable of almost complete disruption of cellular structures and denaturation.
- Used for solubilization of a wide variety of proteins, including membrane proteins, for electrophoretic separation.
- Detergent molecules tightly bind with the protein molecules masking their native charge and rendering the protein molecules the overall negative charge of the ionic detergent.