Type: Zwitterionic detergent
Full Name: 3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate
Molecular Formula: C
32H
58N
2O
8S
Molecular Weight: 630.9
Form: White solid
Purity: >99%
Solubility: Water soluble
Conductivity: <50µS in a 10% solution
Critical micelle concentration (CMC): 8mM (25°C)
Aggregation number: 11
Cloud point: 90°C
Average micellar weight: 7000
Applications
- Zwitterionic detergent.
- Non-denaturing.
- Electrically neutral.
- Higher solubility than CHAPS because of a more polar head group.
- Solubilizes membrane proteins in their native state.
- Solubilizes opiate receptor to a state exhibiting reversible binding of opiates.