TrueBlot® Biotin magnetic beads can be used in immunoassays or molecular diagnostics when avidin or streptavidin is bound to proteins or oligonucleotides. Biotin magnetic beads can also be used in nucleic acid isolation, protein purification, and cell separations. Biotin magnetic particles are incubated with the avidin or streptavidin labeled solution and then separated by magnets. After the unbound particulates are washed from the particles, the bound avidin are eluted from the particles using the elution buffer. The particles are then magnetically separated from the eluted solution, which is removed manually.