Infliximab with the brand name of Remicade, is a chimeric monoclonal IgG1 antibody. It binds to TNF-α, which is a key proinflammatory cytokine involved in chronic inflammatory diseases. Infliximab functions as TNF-α blocker to disrupt the interaction of TNF-α with its receptors.
GenScript Anti-Infliximab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Infliximab.
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Synonyms: Rabbit polyclonal to Infliximab/Remicade
Description: Infliximab with the brand name of Remicade, is a chimeric monoclonal IgG1 antibody. It binds to TNF-α, which is a key proinflammatory cytokine involved in chronic inflammatory diseases. Infliximab functions as TNF-α blocker to disrupt the interaction of TNF-α with its receptors. GenScript Anti-Infliximab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Infliximab.
Host Species: Rabbit
Conjugation: Unconjugated
Immunogen: Infliximab
Purification: Antigen affinity column
Properties
- Concentration 0.5 mg/ml, lyophilized with PBS, pH 7.2, containing 0.02% sodium azide.
- Reconstitution Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/ml.
- Specificity The product is specific for Infliximab.
- Storage The lyophilized product remains stable up to 1 year at -20 °C from date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid repeated freezing and thawing cycles.
- Note GenScript can customize this product per customer's request including product size, buffer components, etc.
Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
ELISA detection: 0.001-0.1µg/ml
Other applications: user-optimized