Creatinine, the end product of creatine catabolism is a normal constituent of urine; daily output about 25 mg/kg body weight. The increased amounts in the urine are typically associated with substantially impaired renal function. Also found together with creatine in muscle tissues and blood. It reacts with picric acid under alkaline conditions to form a Janovski complex. The rate of formation of the colored complex, measured at 480-520 nm is proportional to the creatinine concentration.
Creatinine is a useful marker for normalizing levels of other molecules found in urine and the altered creatinine levels may be associated with conditions that result in decreased renal blood flow, such as diabetes and cardiovascular disease.
Grade: ANHYDROUS
Purity: 98.5 - 102.0%
Key Applications: Marker for the renal function
Application Areas: Diagnostic
Product Type: Biochemicals
Biochemical Category: Pharmaceuticals
Density: 1.09 g/cm3 (Lit.)
Melting Point: 295°C (Lit.)
Presentation: White powder
Format: Powder
pH: 7.5 - 9.0 (5% aq soln)
Heavy Metals: <0.001%
Loss on Drying: <3.0%
Residue on ignition: <0.2%
Solubility: Soluble in 12 parts water; slightly soluble in ethanol; practically insoluble in acetone, ether, chloroform.
Storage & Handling: Room Temperature