p-Coumaric acid is a hydroxycinnamic acid, an organic compound that is a hydroxy derivative of cinnamic acid. There are three isomers of coumaric acid- o-coumaric acid, m-coumaric acid, and p-coumaric acid- that differ by the position of the hydroxy substitution of the phenyl group.
p-Coumaric acid was used as a substrate to study the enzyme activity of 4-hydroxyphenylacetate 3-hydroxylase (4HPA3H) found in E.coli which inturn was used in biosynthesis of caffeic acid . Phenylpropanoids (p-Coumaric acid) esterified with sucrose was essential for higher antimicrobial activity of vanicosides . The FSI (flavone synthase I) - expressing recombinant strain produced 50% more apigenin and six times less naringenin than the FSII (membrane-bound flavone synthase II) - expressing recombinant strain when p-coumaric acid was used as a precursor phenylpropanoid acid.
Purity: ≥98%
Key Applications: Substrate, Precursor of phenylpropanoid acid
Application Areas: Microbiology
Product Type: Biochemicals
Melting Point: 212 - 222°C
Presentation: White to tan powder
Format: Powder
NOTES: Predominantly trans-isomer
Solubility: Soluble in hot water, ethanol, ether; slighly soluble in cold water; practically insoluble in benzene (25 mg/ mL - clear colorless).
Storage & Handling: Room Temperature