MCP-3, CCL7, murine (mouse): Murine CCL7, also known as MARC, is belonging to the CC chemokine family.
It is encoded by the gene CCL7 and was isolated from a mouse mast cell line after Fc epsilon RI triggering by IgE plus antigen.
Sequence comparisons suggest that MARC may be the mouse homologue of the human MCP-3 gene.
Similar to the human system, MARC/FIC is postulated the murine MCP-3.
The MCP-3 protein family signals through CCR2 expect MCP-1 and possess cross-reacts across species.
CCL7/MCP3 has chemotactic function for monocytes and eosinophils, but not for neutrophils., UnitProt ID: Q03366