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Bio Basic Inc.

IL-2, Porcine

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IL-2, Interleukin-2, porcine: IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation.

It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils.

IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response.

The receptor for IL-2 consists of three subunits (55 kDa IL2Rα, 75 kDa IL2Rβ, 64 kDa common gamma chain γc/IL2Rγ) that are present on the cell surface in varying preformed complexes.

Recombinant porcine IL-2 is a 15.3 kDa protein containing 134 amino acid residues and it shares about 72 % amino acid sequence identity with mouse, human and rat IL-2.

It also shares 60 % and 67 % acid sequence identity with rhesus macaque and equus caballus IL-2, respectively., UnitProt ID: P26891

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Product Detail
Thomas No.
C861U74
Mfr. No.
RC282-13.SIZE.1mg
Description
IL-2, Porcine, 1mg
list price/quantitytotal
$0.00
$0.00 (0 Items)
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