The BIO-WORLD Abundant Protein Removal-Haptoglobin kit removes the high-abundant protein- Haptoglobin from human serum and plasma. The high affinity-based column contains separopore-matrix coupled with antibodies against the serum protein.
The presence of abundant proteins in human serum and plasma often masks the detection of low-abundant proteins of interest that serve as biomarkers for disease when being studied by 2D gel electrophoresis or LC/MS. After depletion of these high-abundant proteins, serum samples consist of an enriched pool of low-abundant proteins that can be further studied without significant interferences with abundant proteins. The Abundant Protein Removal-Haptoglobin kit provides a binding capacity of 2 mg abundant protein per column.