Antigen: synthetic peptide from rat PDI conjugated to KLH
Host: rabbit
Cross Reactivity: (+) human, mouse, rat, canine, hamster, monkey, guinea pig, bovine, ovine, porcine, and Xenopus PDI
Application(s): ICC, IHC, IP, and WB
PDI is involved in disulphide-bond formation via its oxidase activity and isomerization via its isomerase activity, as well as the reduction of disulphite bonds in proteins. Studies suggest BiP and PDI work together sequentially to increase oxidation of these proteins.