EICOSANOIDS-EIA (Enzyme Immunoassay) Products (64)

Compare Tool

Select up to 3 products

  • Thumbnail Image for Leukotriene C4 ELISA Kit

    Cayman Chemical
    Item #:
    C790U10-TS

    Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in eosinophils, mast cells, and macrophages. Their biosynthesis proceeds via the 5-lipoxygenase (5-LO) pathway in which 5-LO converts arachidonic acid into LTA4 with 5(S)-HpETE as an intermediate. The...

  • Thumbnail Image for Prostaglandin D2-MOX Express ELISA Kit
    Item #:
    C790T42-TS

    Cayman’s PGD2-MOX Express ELISA is a competitive assay that permits the rapid measurement of PGD2 from biological samples, requiring only 1 hour incubation and development times for each step. The methodology for the assay is the same as that employed in the PGD2-MOX ELISA (Item No. 512011)....

  • Thumbnail Image for sPLA2 (Type V) Inhibitor Screening Assay Kit
    Item #:
    C837X51

    The sPLA2 (Type V) Inhibitor Screening Assay is a convenient colorimetric assay designed for rapid screening of Type V sPLA2 inhibitors in a 96-well format. Each kit contains assay buffer, DTNB, diheptanoyl thio-PC, human sPLA2 (Type V), a 96-well plate, plate cover, and complete instructions.

  • Thumbnail Image for COX-2 (human) Inhibitor Screening Assay Kit
    Item #:
    C789C44

    COX-1 and COX-2 catalyze the production of the PG and TX precursor PGH2. COX-2 is primarily responsible for the biosynthesis of PGs under acute inflammatory conditions. The COX-2 (human recombinant) Inhibitor Screening Assay measures PGF2α that is produced by SnCl2 reduction of COX-2-derived...

  • Thumbnail Image for Prostaglandin D2 ELISA Kit

    Cayman Chemical
    Item #:
    C790U95-TS

    Prostaglandin D2 (PGD2) is biosynthesized in the brain by a soluble, 26 kDa glutathione-independent lipocalin-type PGD2 synthase. This PGD2 accumulates in the cerebrospinal fluid (CSF), where it induces physiologic sleep in rats and humans. PGD2 is also synthesized in mast cells and leukocytes by a...

  • Thumbnail Image for COX Fluorescent Activity Assay Kit
    Item #:
    C789B73

    Cayman’s COX Fluorescent Activity Assay provides a convenient fluorescence-based method for detecting COX-1 or COX-2 activity in both crude (cell lysates/tissue homogenates) and purified enzyme preparations. The assay utilizes the peroxidase component of COXs. In this assay, the reaction...

  • Thumbnail Image for EP2 Receptor (rat) Reporter Assay Kit
    Item #:
    C790X71

    The EP2 receptor is one of four GPCRs that mediate the actions of PGE2. The diverse effects of PGE2 acting via EP2 receptors point to the need to identify novel agonists and antagonists, both to further elucidate the function of this receptor subtype and for use as therapeutics for various diseases....

  • Thumbnail Image for Prostaglandin D2-MOX ELISA Kit
    Item #:
    C790U91-TS

    This PGD2-MOX ELISA is based on the conversion of PGD2 to a stable MOX derivative. Treatment of the sample with MOX HCl converts PGD2 into PGD2-MOX, preventing its further chemical degradation. The antiserum used in the assay was developed using conjugates of this derivative and is very specific for...

  • Thumbnail Image for EP4 Receptor (rat) Activation Assay Kit (cAMP)
    Item #:
    C790X75

    The EP4 receptor is one of four GPCRs that mediate the actions of prostaglandin E2 (PGE2). The diverse effects of PGE2 acting via EP4 receptors point to the need to identify novel agonists and antagonists, both to further elucidate the function of this receptor subtype and for use as therapeutics...

  • Thumbnail Image for COX-1 (ovine) Inhibitor Screening Assay Kit
    Item #:
    C789C45

    COX-1 and COX-2 catalyze the production of the PG and TX precursor PGH2. COX-2 is primarily responsible for the biosynthesis of PGs under acute inflammatory conditions. The COX-1 (ovine) Inhibitor Screening Assay measures PGF2α that is produced by SnCl2 reduction of COX-1-derived PGH2....

  • Thumbnail Image for COX (ovine) Inhibitor Screening Assay Kit
    Item #:
    C790V95

    The COX (ovine) Inhibitor Screening Assay directly measures PGF2α produced in the cyclooxygenase reaction. The prostanoid product is quantified via ELISA using a broadly specific antibody that binds to all the major prostaglandin compounds. Thus, this Cayman COX Assay is more accurate and...

  • Thumbnail Image for Maresin 1 ELISA Kit

    Cayman Chemical
    Item #:
    C790U32-TS

    Maresins (macrophage mediators in resolving inflammation) are members of a class of potent anti-inflammatory and pro-resolving mediators that are synthesized by macrophages in the presence of DHA. MaR1 is produced via oxidation of endogenous DHA by 12-LO. MaR1 has been shown to reduce neutrophil...

  • Thumbnail Image for 13,14-dihydro-15-keto Prostaglandin F2a ELISA Kit
    Item #:
    C790V55-TS

    PGF2α is rapidly metabolized to 13,14-dihydro-15-keto PGF2α in vivo, by the enzymes 15-hydroxy PG dehydrogenase and D13-reductase. Measurement of 13,14-dihydro-15-keto PGF2α in plasma can be used as a marker of the in vivo production of PGF2α. The Cayman’s...

  • Thumbnail Image for Lipid Hydroperoxide (LPO) Assay Kit
    Item #:
    C789D54

    Cayman’s Lipid Hydroperoxide Assay measures the hydroperoxides directly utilizing the redox reactions with ferrous ions. An easy to use quantitative extraction method was developed to extract lipid hydroperoxides into chloroform, and the extract is directly used in the assay. This procedure...

  • Thumbnail Image for Prostaglandin I Metabolite ELISA Kit
    Item #:
    C790U17-TS

    Prostaglandin I (Prostaglandin I2; PGI2) is a potent vasodilator and inhibitor of platelet aggregation that is formed from arachidonic acid primarily in the vascular endothelium and renal cortex by sequential activities of cyclooxygenase (COX) and PGI2 synthase. It is non-enzymatically hydrated to...

  • Thumbnail Image for FABP4 Inhibitor/Ligand Screening Assay Kit
    Item #:
    C835U87

    Cayman’s FABP4 Ligand Binding Assay provides a simple, reproducible, and sensitive tool for the identification of FABP4 ligands. The assay makes use of a detection reagent that exhibits increased fluorescence at 500 nm when bound to FABP4. Any strong ligand and/or inhibitor of FABP4 will...

Compare Tool

Select up to 3 products

Please Log In

Don't have a web profile? Create one now.