- A three-dimensional model of basement membrane that promotes differentiation of a variety of cell types, especially epithelial, endothelial, muscle, and neuronal cells
Corning® Matrigel®™ Matrix is a reconstituted basement membrane isolated from the Engelbreth-Holm-Swarm (EHS) mouse sarcoma, a tumor rich in extracellular matrix proteins. This matrix is composed of laminin, collagen iv, entactin (nidogen), and heparan sulfate proteoglycan (perlecan). Growth factors, collagenases, plasminogen activators, and other undefined components have also been reported to be found in Corning® Matrigel® Matrix.
Corning® BioCoat™ Matrigel®™ Matrix Cellware is a line of tissue culture vessels with a uniform application of Corning® Matrigel®™ Matrix. This cellware is manufactured in a highly controlled environment and rigorously tested to assure product consistency and performance.
Applications include:
- Elicitation of tissue-specific cellular morphology and protein production in epithelial cells
- Differentiation of endothelial, muscle, and neuronal cells
- Development of three-dimensional matrix model systems
Quality Control: Corning® BioCoat™ Matrigel®™ Matrix Cellware is tested for ability to promote neurite outgrowth from chick dorsal root ganglia (in the absence of NGF). Tested and found negative for bacteria and fungi
Storage and Stability: Corning® BioCoat™ Matrigel®™ Matrix Cellware is stable for at least three months at -20°C. Keep frozen until use. Corning® BioCoat™ Matrigel®™ Matrix Cellware, thin layer is stable for at least three months at 2-8°C.