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GenScript

GDNF, Human

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Glial cell line-derived neurotrophic factor (GDNF) is a neurotrophic factor belonging to the TGF-beta super family and is necessary for neuron survival and phenotypic maintenance in the central and peripheral nervous systems. G-DNF has the potential to support the differentiation and survival of many neuron subpopulations, especially dopaminergic neurons and motor neurons, as well as Purkinje cells and sympathetic neurons. Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes and skeletal muscle cells are known to express GDNF in human. GDNF has been shown to interact with GFRA2 and GDNF family receptor alpha 1. Mutations in this gene may be associated with Hirschsprung's disease, Parkinson's disease and amyotrophic lateral sclerosis (ALS).
The recombinant human G-DNF expressed in E.coli is a disulfide-linked homo-dimer, with an apparent molecular weight of 17 kDa.

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Product Detail
Thomas No.
C744X01
Mfr. No.
Z03387-1
Description
GDNF, Human,1mg

list price/quantitytotal
$0.00
Thomas No.
C744X02
Mfr. No.
Z03387-10
Description
GDNF, Human,10µg

list price/quantitytotal
$0.00
Thomas No.
C744X03
Mfr. No.
Z03387-50
Description
GDNF, Human,50µg

list price/quantitytotal
$0.00
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Product is restricted and can only be purchased by customers with a web profile linked to a Thomas Business Account - Click here to login or create your web profile. If you do not have a Thomas Business Account, please Contact Us and someone will respond with details on how to apply for a business account with us.

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