A three-dimensional model of basement membrane that promotes differentiation of a variety of cell types, especially epithelial, endothelial, muscle, and neuronal cells
BD Matrigel Matrix is a reconstituted basement membrane isolated from the Engelbreth-Holm-Swarm (EHS) mouse sarcoma, a tumor rich in extracellular matrix proteins. This matrix is composed of laminin, collagen IV, entactin (nidogen), and heparan sulfate proteoglycan (perlecan). Growth factors, collagenases, plasminogen activators, and other undefined components have also been reported to be found in BD Matrigel Matrix.
BD BioCoat Matrigel Matrix Cellware is a line of tissue culture vessels with a uniform application of BD Matrigel Matrix. This cellware is manufactured in a highly controlled environment and rigorously tested to assure product consistency and performance.
Applications include:
Elicitation of tissue-specific cellular morphology and protein production in epithelial cells
Differentiation of endothelial, muscle, and neuronal cells
Development of three-dimensional matrix model systems
Quality Control:
BD BioCoat Matrigel Matrix Cellware is tested for ability to promote neurite outgrowth from chick dorsal root ganglia (in the absence of NGF). Tested and found negative for bacteria and fungi
Storage and Stability:
BD BioCoat Matrigel Matrix Cellware is stable for at least three months at -20°C. Keep frozen until use. BD BioCoat Matrigel Matrix Cellware, thin layer is stable for at least three months at 2-8°C.
Multiwell Plates
Culture Dishes
Thin-Layer Multiwell and Assay Plates
Thin-Layer Culture Dishes
Hepatocytes
Growth Factor Reduced Matrigel™ Matrix for Smooth Muscle Cells