• Promotes cell adhesion, proliferation, and differentiation of a variety of cell types, particularly neurons, epithelial cells, myocytes, and myoblasts
Laminin, a major structural component of basement membranes, is a 900 kD glycoprotein composed of three polypeptide chains with a multidomain structure. Laminin has many varied functions that are mediated by binding to various components of the basement membrane (e.g., Collagen IV and heparan sulfate proteoglycan) and to cell surface receptors.
BD BioCoat Laminin Cellware tissue culture vessels with a uniform application of mouse laminin. This Cellware is manufactured in a highly controlled environment and rigorously tested to assure product consistency and performance.
Applications include:
• Promotion of cell attachment and spreading
• Induction of cell differentiation and neurite outgrowth
• Increased proliferation of myoblasts
• Studies of effects of laminin on cell behavior
• Cell adhesion assays
Quality Control:
Tested for ability to initiate differentiation (neurite outgrowth) of NG-108 rat glioma/mouse neuroblastoma cells. Tested and found negative for the presence of bacteria and fungi. Laminin purity >90% by SDS-PAGE (contains entactin)
Storage and Stability:
Stable for at least three months at 2-8°C. Do not freeze.
Multiwell and Assay Plates
Culture Dishes
Culture Flasks
