Sodium bicarbonate is broadly used as a physiological buffer in cell culture applications. The pKa for bicarbonate <-> carbonic acid reaction is 6.4 The pKa for bicarbonate <-> carbonate reaction is 10.3. Sodum bicarbonate has two pKas, 6.4 and 10.3. The compound can react with both…

Sodium nitroprusside dihydrate reagent used for chromatographic detection of peptides containing cystine. Also liberates nitric oxide in biological systems. Sodium nitroprusside dihydrate was used in the digital image analysis for the determination of products of simple colorimetric tests for…

IPTG (isopropyl-β-thiogalactoside) is an analogue of allolactose that binds specifically to the repressor protein of the lac operon and induces expression of β-galactosidase in Escherichia coli. IPTG is a commonly used reagent in cloning procedures that require induction of…

Alanine is a nonessential amino acid that plays a key role in the glucose-alanine cycle between muscle tissue and the liver. In amino acid-degrading tissues such as muscle, amino groups are pooled as glutamate by transamination reactions. Used as an amino donor in conversion of…

Sodium azide is used as a preservative for laboratory reagents; a bacteriostatic agent in storage solutions. Inhibits gram negative flora so is therefore included in culture media for the selective isolation of Streptococci and Staphylococci. It has been used to avoid bacterial contamination during…

Non-essential amino acid for human development; referred to as an excitatory amino acid (EAA) due to its role in neurotransmission. L-Glutamic Acid Monosodium Salt is used as a neurotransmitter at fast synapses; agonist at kainate, NMDA and quisqualate receptors. Agonist at kainate, NMDA, and…

Vitamin B12 (cobalamin) refers to a group of chemically-related cobalt containing molecules involved in cell processes such as DNA synthesis, fatty acid synthesis, energy production and regulation. The physiologically active forms of vitamin B12 include methylcobalamin and adenosylcobalamin,…

MAO inhibitor; inhibits platelet aggregation.

1,1,1,3,3,3-Hexafluoro-2-propanol is polar and exhibits strong hydrogen bonding properties enabling it to dissolve substances that serve as hydrogen-bond acceptors. 1,1,1,3,3,3-Hexafluoro-2-propanol is a polar solvent of high ionizing power and facilitates Friedel–Crafts-type reactions, using…

p-Aminobenzoic acid is an organic compound used in the treatment of fibrotic skin disorders like Peyronie's disease. It is employed as an intermediate in the synthesis of folate (Vitamin BX), azo dyes and cross linking agents. It is also useful in biomedical sector for the preparation of local…

5-Bromo-2’-deoxyuridine is a thymidine analog and useful for the study of DNA synthesis where it is incorporated into DNA in place of thymidine. Measure DNA synthesis Label dividing cells Study cell signaling and processes that induce cell proliferation Used as a mutagen in…

Imidazole is a chelator for the binding of various divalent cations. Imidazole is a highly polar, planar 5 membered ring. It is amphoteric in nature. Imidazole can be used for the elution of histidine containing proteins from divalent cation resins and can also be used in reverse staining of…

Borax is a salt of boric acid which is used as a buffer. It has a co-complexing ability with other agents in water to form complex ions with various substances. It is also commonly utilized in chromatography and electrophoresis studies. Borax is typically used as a buffer component,…

Hexadecane (n-Hexadecane) is an aliphatic long-chain hydrocarbon. It is a reference fuel with the cetane number 100 and is employed in determining the cetane number of diesel fuels. The mechanism of the oxidation of hexadecane in the gas-phase has been described. The density, speed of sound,…

Sorbic acid (2,4-hexadienoic acid) is a straight chain unsaturated fatty acid. It is an antimicrobial agent. The antimicrobial action of sorbic acid is due to its inhibitory influence on various enzymes in the microbial cell such as enzymes involved in carbohydrate metabolism such as enolase and…

Physiological chelating agent for heavy metals. It is used as an antirheumatic and as a chelating agent in Wilson′s disease. It is used as a copper chelator to form mixed disulfides with cysteine or other sulfide media components. It is used to inactivate protein-1 DNA binding and to…

Dimethyl sulfoxide is a dipolar, aprotic solvent. Has been shown to accelerate strand renaturation (1-10% concentration) and is believed to give the nucleic acid thermal stability against depurination. By heating the solid form to approximately 30°C, the product can be melted without harming…

Ethylenediamine Tetraacetic Acid is a polyamino carboxylic acid hexadentate ligand and a chelating agent. Ethylenediamine Tetraacetic Acid is a chelator of divalent cations. It also inhibits enzymes, such as metalloproteases, that require divalent cations for activity. Zinc-dependent…

L-Ascorbic Acid, Sodium Salt is a vitamin widely distributed in the plant and animal kingdom. L-Ascorbic Acid, Sodium Salt is used as an antimicrobial and antioxidant in foodstuffs, a reductant for the isolation of chloroplasts. It has an effect on the nonspecific immune system. It preserves…

L-Tryptophan is an amino acid precursor of serotonin and melatonin.

Potassium phosphate is a reagent with high buffering capacity. It occurs in several forms: monobasic, dibasic, and tribasic (K3PO4). Most pH neutral potassium phosphate buffer solutions consist of mixtures of the monobasic and dibasic forms to varying degrees, depending on the desired pH. …

p-Toluenesulfonic acid monohydrate is an organic-soluble acid catalyst in organic synthesis. The catalyst has been incorporated in the esterification of carboxylic acids or transesterification of esters. p-Toluenesulfonic acid monohydrate has been used as a reducing agent for the reductive…

Acetic Acid, Glacial is an excellent solvent for many organic compounds. Acetic acid is widely used in manufacturing either as starting material or as a solvent. In the food industry, dilute solutions are used for preparation and preservation. Because acetic acid is a weak acid, it is effective as…

Fructose, or fruit sugar, is a simple monosaccharide found in many plants. It is one of the three dietary monosaccharides, along with glucose and galactose, that are absorbed directly into the bloodstream during digestion. Fructose is a 6-carbon polyhydroxyketone. It is an isomer of glucose which…

Palmitic acid, or hexadecanoic acid is one of the most common 16 carbon saturated fatty acids found in animals and plants. It occurs as the glyceryl ester in many oils and fats. Palmitic acid has been reported to target proteins to cell membranes. It has been found to promote triglyceride…

Undecane is a liquid alkane hydrocarbon. Undecane may be used as an internal standard in gas chromatography when working with other hydrocarbons. Since the boiling point of undecane (196°C) is well known, it may be used as a comparison for retention times in a gas chromatograph for molecules…

Triethanolamine is a zwitterionic buffer. Triethanolamine(TEA) is used primarily as an emulsifier and surfactant. It neutralizes fatty acids, adjusts and buffers the pH, and solubilises oils and other ingredients that are not completely soluble in water. Triethanolamine is also used as organic…

Spermidine is biogenic polyamine formed from putrescine, a precursor of spermine. Spermidine has a role in cell growth processes and the formation and interconversion of spermidine in mammalian cells has been reported. Spermidine binds to and activates NMDA(N-Methyl-D-Aspartate receptor) and has…

SDS is an anionic detergent and wetting agent that is effective in both acid and alkaline solutions. Most proteins bind SDS in a ratio of 1.4 grams SDS to 1 gram protein. The charges intrinsic to the protein become insignificant compared to the overall negative charge provided by the bound SDS. The…

Stearic acid is a long-chain saturated fatty acid that can be derived from either animal fats or vegetable oils. Compared to other long-chain saturated fatty acids that are hypercholesterolemic, experimental diets high in stearic acid (9.3-11.8% of energy) do not raise plasma total cholesterol or…

Cholesterol is the principal sterol of the higher animals, found in all body tissues. It is the main constituent of gallstones and all biological membranes. Approximately 25% of total brain lipid is cholesterol. Cholesterol is suitable for use in liposome preparations.