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  • Atriopeptin III

    LKT Labs

    Atriopeptin III is an analog of atrial natriuretic peptide (ANP) that exhibits vasodilatory/hypotensive and diuretic activities. In rat kidneys, atriopeptin III increases the diameter of constricted afferent arterioles, decreasing blood pressure.

  • AS-605240

    LKT Labs

    AS-605240 is an inhibitor of p110δ PI3K that exhibits anti-inflammatory, immunosuppressive, and anti-diabetic activities. In animal models, AS-605240 inhibits the development of or reverses the progression of experimental autoimmune encephalitis (EAE). AS-605240 also inhibits the development…

  • Amylin, rat

    LKT Labs

    Amylin is also known as islet amyloid precursor peptide (IAPP) and is co-secreted with insulin from pancreatic ß-cells. Amylin is an endogenous peptide hormone that exhibits gastrointestinal motility modulating activity, decreasing gastric emptying and suppressing gastric acid secretion; these…

  • Adrenomedullin (13-52), human

    LKT Labs

    Adrenomedullin is an endogenous peptide hormone involved in growth and differentiation of stem cells. This peptide exhibits vasodilatory, natriuretic, and cardioprotective activities. Adrenomedullin decreases blood pressure and increases neovascularization. This peptide binds microtubule-associated…

  • Asiaticoside

    LKT Labs

    Asiaticoside is a triterpene found in Centella that exhibits anti-inflammatory, neuroprotective, cognition enhancing, antipyretic, antioxidative, pro-angiogenic, anticancer chemotherapeutic, and chemopreventive activities. Asiaticoside inhibits melanogenesis by decreasing DNA binding by MITF; as a…

  • Antiestrogen Peptide

    LKT Labs

    This peptide is a 12-amino acid peptide that exhibits antiestrogen-like effects. Grade: ≥95%

  • Atosiban Acetate

    LKT Labs

    Atosiban is an antagonist at oxytocin and vasopressin receptors, exhibiting tocolytic activity. Atosiban is clinically used to decrease uterine contractility in the prevention of preterm birth.

  • Artesunate

    LKT Labs

    Artesunate is a sesquiterpene lactone derived from Artemisia. Artesunate exhibits anticancer chemotherapeutic, antiviral, anti-angiogenic, and anti-parasitic activities. Artemisinins such as artesunate are best known for their antimalarial activity. Artesunate induces G0/G1 phase cell cycle arrest,…

  • ARRY-162

    LKT Labs

    ARRY-162 is an orally bioavailable noncompetitive inhibitor of MEK1/2 and ERK that shows anticancer chemotherapeutic activity. Inhibition of MEK inhibits downstream signaling by IL-1, IL-6, and TNF. ARRY-162 inhibits proliferation in melanoma, non-small-cell lung cancer (NSCLC), head/neck cancer,…

  • Aflatoxin M1

    LKT Labs

    Aflatoxins are mycotoxins found in foods and livestock feeds that were initially produced by species of Aspergillus. Aflatoxin M1 is the hydroxylated metabolite of aflatoxin B1; it inhibits DNA synthesis and induces cell cycle arrest.

  • Adenosine Triphosphate Disodium Hydrate

    LKT Labs

    Adenosine triphosphate (ATP) disodium is clinically used to inhibit reperfusion injury after myocardial infarction during percutaneous coronary intervention; it also improves left ventricular function in clinical settings. ATP itself is a coenzyme and unit of cellular energy. ATP is required for…

  • Atracurium Besylate

    LKT Labs

    Atracurium is a reversible inhibitor of acetylcholine receptors (AChRs) that acts as a non-depolarizing neuromuscular junction blocker (NMJ); it causes muscular paralysis and is clinically used as an anesthetic.

  • N(a),N(a)-Dimethyl-L-Arginine Ammonium

    LKT Labs

    Na,Na-Dimethyl-L-arginine is also known as asymmetrical dimethyl-L-arginine (ADMA). This compound is an endogenous inhibitor of NOS and is involved in the regulation of the water/sodium balance. High levels of ADMA are associated with obesity, atherosclerosis, renal disease, and coronary artery…

  • Benzyl Selenocyanate

    LKT Labs

    Benzyl selenocyanate is an organoselenium compound found in selenium-enriched garlic. Benzyl selenocyanate exhibits chemopreventive activity. This compound inhibits carcinogenesis induced by DMBA, azoxymethane, or benzo[a]pyrene in various animal models. Benzyl selenocyanate may also inhibit DNA…

  • 2B-(S)

    LKT Labs

    2B-(S) is a 16-amino acid peptide conjugated to biotin.

  • Beauvericin

    LKT Labs

    Beauvericin is a cyclic hexadepsipeptide mycotoxin initially produced by species of Cordyceps. Beauvericin exhibits pro-oxidative and anticancer activities. In colon adenocarcinoma cells, beauvericin induces oxidative stress by increasing ROS levels and decreasing glutathione levels and also…

  • Acetylsalicylic Acid

    LKT Labs

    NSAID and COX-1/2 inhibitor used to decrease inflammation. It inhibits platelet aggregation and prolongs bleeding time by decreasing levels of thromboxane A2. Chronic administration decreases risk of cancer and cardiovascular events.

  • Aztreonam

    LKT Labs

    Aztreonam is a synthetic ß-lactam antibiotic that displays antibacterial activity against gram negative bacteria. Like similar compounds, aztreonam inhibits penicillin binding proteins.

  • Auriculin A

    LKT Labs

    Auriculin A is a synthetic form of atrial natriuretic peptide (ANP) that exhibits cardiomodulatory, vasodilatory/hypotensive, diuretic, and natriuretic activities. In vivo, auriculin A decreases mean blood pressure and increases perfusion pressure and sodium excretion.

  • Azelastine Hydrochloride

    LKT Labs

    Azelastine is a second generation antihistamine that inhibits H1 histamine receptors. Azelastine exhibits anti-allergic, anti-inflammatory, and anti-tussive activities and is clinically used to treat allergic rhinitis. Azelastine activates transient receptor potential vanilloid 1 (TRPV1) channels,…

  • Atriopeptin II, rat/rabbit/mouse

    LKT Labs

    Atriopeptin II is an analog of atrial natriuretic peptide (ANP) that exhibits vasodilatory/hypotensive and anxiolytic activities. Like other ANP analogs, atriopeptin II decreases blood pressure. This peptide also exhibits anxiety-lowering benefit in animals undergoing testing in the elevated plus maze.

  • Aristolochic Acid C

    LKT Labs

    Aristolochic acid C is a carcinogenic compound found in Aristolochia and Radix that has commonly been used in traditional Chinese medicine.

  • Asperosaponin VI

    LKT Labs

    AS-703026 is an inhibitor of MEK1/2 that exhibits anticancer chemotherapeutic activity. In vitro, AS-703026 inhibits proliferation of melanoma cells. In both in vitro and in vivo models of colorectal cancer containing WT Ras or mutant KRAS, AS-703026 inhibits growth of cells and also of tumors.…

  • Aripiprazole

    LKT Labs

    Aripiprazole is a second generation atypical antipsychotic that also exhibits neuromodulatory, antidepressant, anxiolytic, antipsychotic, cognition enhancing, and antioxidative activities. Aripiprazole acts as a partial agonist at D2 receptors and 5-HT1A receptors and as an antagonist at 5-HT2A…

  • Dihydroartemisinin

    LKT Labs

    Dihydroartemisinin is a sesquiterpene lactone that can be derived from Artemisia. Dihydroartemisinin exhibits anticancer, antiviral, anti-inflammatory, anti-asthma, and anti-parasitic activities. Artemisinins such as dihydroartemisinin are best known for their antimalarial activity.…

  • L-(+)-Ascorbic Acid

    LKT Labs

    L-Ascorbic acid is a vitamin C compound that can be found in many food and plant sources. L-Ascorbic acid exhibits antioxidative benefit and reducing activity; in vitro, it can act as a prolyl hydroxylase cofactor. Grade; ≥98%

  • Ascorbyl Palmitate

    LKT Labs

    Ascorbyl palmitate is a fat-soluble vitamin C derivative that is commercially used as a vitamin C supplement and antioxidative food additive; it is also used in research models to aid in drug delivery or tissue targeting. Ascorbyl palmitate is the ester of ascorbic acid and palmitic acid. In…

  • AS-252424

    LKT Labs

    AS-252424 is an inhibitor of p110γ PI3K that exhibits anti-inflammatory activity. In animal models of peritoneal inflammation, AS-252424 decreases leukocyte recruitment. In vascular smooth muscle cells, AS-252424 decreases endothelin A receptor-mediated activity of transient receptor…

  • ß-Amyloid Peptide (1-40)

    LKT Labs

    Amyloid-ß (Aß) is a peptide cleavage product of amyloid precursor protein (APP) that is often used as a biomarker in Alzheimer’s disease. Misfolded Aß oligomers instigate conformation changes in other, normally folded Aß oligomers, increasing the number of misfolded proteins and eventually forming…

  • ASP3026

    LKT Labs

    ASP-3026 inhibits anaplastic lymphoma kinase (ALK) and shows anticancer chemotherapeutic activity. Treatment with ASP-3026 lowers tumor burden in lung and intrapleural tumor models.

  • AS-703026

    LKT Labs

    AS-703026 is an inhibitor of MEK1/2 that exhibits anticancer chemotherapeutic activity. In vitro, AS-703026 inhibits proliferation of melanoma cells. In both in vitro and in vivo models of colorectal cancer containing WT Ras or mutant KRAS, AS-703026 inhibits growth of cells and also of tumors.…

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