Ham's F-12 media was originally formulated for the serum-free culture of CHO cells, and is based on Ham's F-10 medium with increased concentrations of choline, inositol, putrescine, and several amino acids.  This medium is also suitable for carcinoma cells, rat skeletal myoblasts,…

A modification of Ham's F-12, F-12K contains higher concentrations of amino acids, sodium pyruvate and other components than the original. It is formulated to support the growth of cells including differentiated rat and chicken cell types and primary human hepatocytes. This medium contains…

Glucose is a main source of energy for living organisms and is used as a nutrient source in cell culture media.  This 45% (w/v) solution has been to ensure no cytotoxicity.

Corning glutagro™, phenol red Named for the site at which it was developed, the Roswell Park Memorial Institute, RPMI 1640 is a modification of McCoy’s 5A containing an increased level of inositol. Examples of cell types for which this medium is appropriate include mammalian myeloma and…

Poly-D-Lysine (PDL) and Poly-L-Lysine (PLL) are synthetic compounds that enhance cell adhesion and protein absorption by altering surface charges on the culture substrate. In addition to promoting cell adhesion, poly-lysine surface treatments support neurite outgrowth and improve the survival of…

Corning extracellular matrices (ECMs) enable researchers to mimic in vivo environments for 2D and 3D cell culture applications. Laminin is a major component of basement membranes. It has numerous biological activities ­including promotion of cell adhesion, migration, chemotaxis, growth, and…

Falcon Cell Culture Insert Companion Plates have been specially designed for use with Falcon or Corning® BioCoat™ Cell Culture Inserts so evaporation and contamination due to improper lid fit is eliminated. In the Feeding Position, pipet access is improved for fluid handling on the…

Laminin (LM), a major component of basement membranes, is a multifunctional glycoprotein that is used as a substrate to culture and maintain differentiated function of a wide variety of cells. Laminin has been shown in culture to stimulate neurite outgrowth, promote cell attachment, chemotaxis,…

Plate-bound antibodies against the T-cell receptor complex have been used to induce activation of T-cells from a variety of species without the help of accessory cells. Corning BioCoat T-Cell activation plates are precoated with high quality BD Pharmingen™ CD3 antibodies. Available for…

Corning BioCoat cell culture inserts are pre-coated with extracellular matrix proteins for applications requiring a protein-coated cell surface, such as cell adhesion, growth, invasion, migration and/or differentiation. Coatings include Corning Matrigel® matrix, Fibronectin, Collagen, and Laminin.

Reagent grade water is ideal for the preparation of reagents, rinsing glassware and plastic ware, cleaning electrodes and other common laboratory tasks requiring highly pure water. No toxic agents, including DEPC, are used in its preparation. The design allows for portability, ease of storage and…

A less complex and extensively modified version of Medium 199, CMRL-1066 was designed initially for use with L-strain cells in unsupplemented culture. It has been used to maintain monolayer growth of permanent cell lines for years without protein supplementation. Although developed for use in…

Sodium bicarbonate Sodium bicarbonate is used as part of a buffering system commonly used to maintain physiological pH 7.2 - 7.4 in a culture environment.  Bicarbonate is a weak buffer with that makes maintaining a pH range of 7.2 - 7.6 somewhat difficult, but it is non-toxic, and is a…

MCDB 131 was originally developed by the researchers Knedler and Ham for the low-protein and serum free growth of human microvascular endothelial cells (HMVEC).  Since its development, this medium has been used for this cell type and others such as liver, smooth muscle, cardiac myocytes. …

Accutase® cell detachment solution contains proprietary marine-origin enzymes with proteolytic and collagenolytic activity for the detachment of primary and stem cell lines and tissues. It’s useful for the routine detachment of cells from standard tissue culture plasticware and adhesion…

Minimum Essential Medium (MEM) is a common cell culture medium developed from early work using Basal Medium Eagle (BME) with normal mammalian fibroblasts and certain subtypes of HeLa cells.  This research indicated that additions made to BME aided cell propagation.  MEM is modified with…

Corning Gentest cryopreserved animal hepatocytes allow researchers to study toxicological and pharmacokinetic properties of new chemical entities (NCEs) in vitro prior to expensive in vivo animal testing. Understanding species differences in metabolism is critical to selecting appropriate…

Named for the site at which it was developed, the Roswell Park Memorial Institute, RPMI 1640 is a modification of McCoy's 5A containing an increased level of inositol. Examples of cell types for which this medium is appropriate include mammalian myeloma and hybridoma cells such as mouse…

This Tryptic Soy Broth (TSB) product is offered for use in sterility testing and validation in the manufacture of a liquid product. The use of this medium in place of the product intended for production allows an accurate assessment of sterility throughout the manufacture process. The product is a…

HTS insert plates are arrays of individual cell culture inserts connected by a rigid, robotics-friendly holder. This single-unit design makes insert plates ideal for running automated, high throughput drug transport (Caco-2 cells) cell toxicity studies or cell migration and invasion studies. …

Blasticidin S HCl is produced by Streptomyces griseochromogenes and inhibits translation in both prokaryotes and eukaryotes, thus preventing the formation of peptide bonds. Appearance: White powder Melting Point: 218.0–225.0°C (424.4-437.0°F) Water Solubility: Soluble

Dulbecco's Phosphate Buffered Saline (DPBS) is a buffer solution which can be used to maintain cell culture media in the physiological pH range of 7.0 to 7.6. It can serve as an irrigating, transporting or diluting fluid while maintaining cell tonicity and viability for a limited period of…

HTS insert plates are arrays of individual cell culture inserts connected by a rigid, robotics-friendly  holder. This single-unit design makes insert plates ideal for running automated, high throughput  drug transport (Caco-2 cells) cell toxicity studies or cell migration and invasion…

Corning extracellular matrices (ECMs) enable researchers to mimic in vivo environments for 2D and 3D cell culture applications. Corning offers a broad range of collagen types that are derived from multiple species. These collagens have been used to culture a variety of cell types to promote…

Human Fibronectin (HFN) is a widely distributed glycoprotein that is used as a substrate to promote attachment of cells through its central-binding domain RGD sequence. HFN is a product of most mesenchymal and epithelial cells and is present in both the ECM and plasma. The principal function of HFN…

This 1:1 mixture of Dulbecco’s Modified Eagle Medium and Ham’s F-12 media is ideal for culture of a variety of cell types under low serum conditions. Dulbecco's Modified Eagle's Medium (DMEM) is a modification of Basal Medium Eagle (BME) containing four-fold concentrations of…

The Corning portfolio of cytokines, growth factors, and media supplementation offers a wide array of proteins that result in proliferation or differentiation of the affected cells. Vialed, highly purified growth factors with high biological activity Broad range of highly purified natural and…

The Corning portfolio of cytokines, growth factors, and media supplementation offers a wide array of proteins that result in proliferation or differentiation of the affected cells. Vialed, highly purified growth factors with high biological activity Broad range of highly purified natural and…

20X Saline-Sodium-Phosphate-EDTA (SSPE) buffer has applications in nucleic acid hybridization and other molecular biology work.

Type IV Collagen is a ubiquitous component in basement membranes and provides the major structural support for this matrix. When the Collagen IV meshwork is assembled, it provides a scaffold for the assembly of other basement membrane components through interactions with laminin, entactin/nidogen,…