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Heterobifunctional Reagents

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  • NHS(N-Hydroxysuccinimidyl)Bromoaceta

    bioWORLD

    Primary amine and sulfhydryl Protein-protein conjugation

  • Sulfo-SANPAH (Sulfosuccinimidyl 6-

    bioWORLD

    Sulfosuccinimidyl 6-(4'-azido-2'-nitrophenylamino)hexanoate Extended chain length, photoactivatable cross-linker Category: Amine-Reactive, Nonselective Photoreactive Reactive Groups nitrophenyl azide and sulfo-NHS-ester Reactive Toward: amino groups Water Soluble: Yes …

  • BSSS(Bis(sulfosuccinimidyl)Suberate)

    bioWORLD

    A popular non-cleavable, membrane-impermeable, water-soluble DSS analog Category: Amine-reactive Reactive Groups: sulfo-NHS-ester Reactive Toward: amino grops Water Soluble: Yes Membrane Permeable: No Cleavability: Non-cleavable MW: 572.43

  • SMPB ( Succinimidyl-4-(p-maleimi.

    bioWORLD

    SMPB, Succinimidyl-4-(p-maleimidophenyl) Butyrate Primary amine and sulfhydryl reactive Enzyme-antibody conjugation Spacer arm

  • Sulfo-MPS (Maleimidopropionic

    bioWORLD

    Sulfo MPS aleimidopropionic acid N-hydroxysulfosuccinimide ester Sulfhydryl reactive Primary amine reactive Water soluble M.W. = 381.27

  • SIAB (N-Succinimidyl (4-iodoacet.

    bioWORLD

    SIAB, N-Succinimidyl (4-iodoacetyl) Aminobenzoate Primary amine and sulfhydryl reactive Enzyme-antibody conjugation

  • Sulfo-EMCS ([N-(E-malemidocaproylox

    bioWORLD

    Sulfo EMCS, [N-(E-malemidocaproyloxy)-sulfosuccinimide] Primary amine reactive Sulfhydryl reactive Water soluble

  • SMCC (Succinimidyl-4-(N-maleimido

    bioWORLD

    SMCC, Succinimidyl-4-(N-maleimidomethyl) cyclohexane-1-carboxylate Primary amine and sulfhydryl reactive Enzyme-antibody conjugation 1,2

  • SPDP (N-Succinimidyl-3-(2-pyridy

    bioWORLD

    SPDP, N-Succinimidyl-3-(2-pyridyldithio) Propionate Primary amine and sulfhydryl reactive Thiolation Cleavable

  • Sulfo-GMBS (N-Maleimidobutyryloxy

    bioWORLD

    Sulfo-GMBS, N-Maleimidobutryloxysulfosuccinimide ester Primary amine reactive Sulfhydryl reactive M.W. 328.24

  • Sulfo-SMPB (Sulfosuccinimidyl 4-

    bioWORLD

    Sulfo SMPB, Sulfosuccinimidyl 4-(p-maleimidophenyl) Butyrate Primary amine and sulfhydryl reactive Spacer arm lenght: 11.6A° Water soluble

  • Sulfo-NHS LC SPDP (Sulfosuccin..

    bioWORLD

    Sulfo NHS LC SPDP, Sulfosuccinimidyl 6-[3-(2-pyridyldithio) propionamido] Hexanoate Water soluble Spacer arm SPDP Antibody-toxin conjugation

  • SANH (Succinimidyl 6-hydrazinonico

    bioWORLD

    SANH (Succinimidyl 6-hydrazinonicotinamide acetone hydrazone) A heterobifunctional crosslinker used to modify amine-containing biomolecules or surfaces to directly incorporate 2-hydrazinopyridine moieties. This reagent, when combined with SFB is ideal for modifying biomolecules in…

  • GMBS (N-Maleimidobutyryloxysuccini

    bioWORLD

    Low potential for eliciting an immune response, ensuring that the primary response is to the antigen-carrier protein conjugate and not against a determinant on the crosslinker. Less immunogenic than SMCC EReactive groups: NHS ester and maleimide Reactive toward: amino and sulfhydryl groups

  • NHS (N-Hydroxysuccinimidyl) lodo

    bioWORLD

    Primary amine and sulfhydryl reactive Protein-protein conjugation

  • Sulfo-SMCC (Sulfosuccinimidyl-4-N

    bioWORLD

    Sulfo-SMCC (Sulfosuccinimidyl-4-N-maleimidomethyl) cyclohexane-1-carboxylate) Synonym: 4-9N-Maleimidomethyl)cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysuccinimide ester sodium Primary amine and sulfydryl reactive Enzyme-antibody conjugation Stable maleimide group

  • MBS (m-Maleimidobenzoyl-N-hydroxy

    bioWORLD

    Heterobifunctional Reactive groups maleimide and NHS ester Primary amine and sulhydryl reactive Hapten-carrier protein conjugation 1,2 Soluble in DMSO and chloroform Storage: Shipped at ambient temperature, upon receipt store at 4°C.

  • SFB (Succinimidyl-p-formyl-benzoate)

    bioWORLD

    SFB (Succinimidyl 4-formylbenzoate) A heterobifunctional crosslinker used to modify amine-containing biomolecules or surfaces to directly incorporate benzaldehyde moieties. This reagent, when combined with SANH (Succinimidyl 6-hydrazinonicotinamide acetone hydrazone) is ideal for modifying…

  • NHS LC SPDP (Succinimidyl 6-[3-(

    bioWORLD

    NHS LC SPDP, Succinimidyl 6-[3-(2-pyridylthio) propionamido] Hexanoate Spacer arm SPDP Antibody-toxin conjugation

  • Sulfo-MBS (m-Maleimidobenzoyl-N-hy

    bioWORLD

    m-Maleimidobenzoyl-N-hydroxysulfosuccinimide ester, Heterobifunctional Useful for coupling proteins, enzymes to antibodies, toxins to antibodies, and haptens to carrier proteins Category: Amine- and Sulfhydryl- Reactive Reactive Groups: sulfo-NHS-ester and maleimide Reactive…

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