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Enzymes & Inhibitors, MP Biomedicals

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MP Biomedicals Enzymes & Inhibitors

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  • Lysozyme from Chicken Eggwhite

    MP Biomedicals

    Lysozyme (muramidase) hydrolyzes preferentially the β-1,4 glucosidic linkages between N-acetylmuramic acid and N-acetylglucosamine which occur in the mucopeptide cell wall structure of certain microorganisms, such as Micrococcus lysodeikticus. Extracts group specific antigens …

  • Lysozyme from Chicken Eggwhite

    MP Biomedicals

    Lysozyme (muramidase) hydrolyzes preferentially the β-1,4 glucosidic linkages between N-acetylmuramic acid and N-acetylglucosamine which occur in the mucopeptide cell wall structure of certain microorganisms, such as Micrococcus lysodeikticus. Extracts group specific antigens …

  • p-Nitrophenyl Phopshate Disodium Salt Hexahydrate

    MP Biomedicals

    p-nitrophenol is suitable for use as a substrate for alkaline and acid phosphatase. p nitrophenol is the substrate of choice for use with alkaline phosphatase in ELISA procedures. This substrate produces a soluble end product that is yellow in color and can be read spectrophotometrically at 405…

  • Pepsin from Porcine

    MP Biomedicals

    Pepsin, an acid protease, contains a proteolytic enzyme. Pepsin contains the "cathepsin" component which has milk curdling activity. It has a broad range of substrate activity and demonstrates an esterase acitivity. It generally attacks peptide bonds. Pepsin is a peptidase used to…

  • Diethyl Pyrocarbonate

    MP Biomedicals

    Clear, Colorless Liquid Synonyms: Diethyl Oxydiformate, Dicarbonic Acid Diethyl Ester, DEPC, Ethoxyformic acid anhydride, Diethyl dicarbonate CAS Number: 1609-47-8 Molecular Formula: C6H10O5 Molecular Weight: 162.1 Beilstein…

  • L-Glutamic Dehydrogenase from Bovine Liver

    MP Biomedicals

    L-glutamic dehydrogenase is a pyridine nucelotide enzyme which catalyzes the reversible oxidative deamination of L-glutamate to α-keto-glutarate and ammonia. L-glutamic dehydrogenase plays a unique role in mammalian metabolism. The reverse reaction catalyzed by this enzyme is the only pathway…

  • Pectin from Apple

    MP Biomedicals

    Pectin is a heterosaccharide, component of terrestrial plant cell walls. Pectin is used as a substrate to identify, differentiate and characterized pectinase(s). It is also used to study its degradation by pectinolytic bacteria.

  • Catalase from Bovine Liver

    MP Biomedicals

    Catalase from bovine liver is a homotetrameric enzyme that is primarily located in peroxisomes. Activates the decomposition of hydrogen peroxide Natural antioxidant used to study roles of reactive oxygen species Catalyzes the decomposition of hydrogen peroxide into water and oxygen …

  • Pancreatin 8X from Porcine Pancreas

    MP Biomedicals

    Pancreatin is a mixture of several digestive enzymes produced by the exocrine cells of the porcine pancreas and delivered to the small intestine for the hydrolysis of complex nutrients. It is a broad-spectrum protease composed of amylase, trypsin, lipase, ribonuclease and protease. Pancreatin…

  • Protease Inhibitor Cocktail Kit

    MP Biomedicals

    Protease Inhibitor Cocktail Kit is a broad spectrum protease inhibitor cocktail which covers both endopeptidases and exopeptidases, non-specific and specific. The cocktail consists of four major protease inhibitors: AEBSF, Sodium EDTA, Leupeptin and Pepstatin A. Protease Inhibitor Cocktail Kit…

  • Acetoacetyl Coenzyme A Trisodium Salt Tetrahydrate

    MP Biomedicals

    Acetoacetyl coenzyme A (Acetoacetyl-CoA) may be used as a substrate for a number of enzymes including; acetoacetyl-CoA thiolase (EC 2.3.1) which produces acetyl-CoA in reverse condensation reaction and (3-Hydroxy-3-methylglutaryl coenzyme A (CoA) synthase (HMGCS)) which produces…

  • Esculin Monohydrate

    MP Biomedicals

    Esculin Monohydrate protects cells against DNA damage and reduces ROS levels. It is also a carcinogenesis inhibitor and displays vitamin P activity. Esculin is a coumarin glycoside that demonstrates antioxidant activitites and protection against chemically-induced carcinogenesis. Esculin is…

  • Catalase from Beef Liver

    MP Biomedicals

    Catalase is an oxidoreductase that catalyzes the conversion of hydrogen peroxide to water and oxygen. Activates the decomposition of hydrogen peroxide Natural antioxidant Used to study roles of reactive oxygen species in gene expression and apoptosis Hydrogen peroxide is a harmful…

  • a-Amylase from Porcine Pancreas

    MP Biomedicals

    α-Amylase isolated from porcine pancreas is a glycoprotein. It is a single polypeptide chain of ~475 residues containing two SH groups and four disulfide bridges and a tightly bound Ca2+ necessary for stability. Chloride ions are necessary for activity and stability. α-Amylase is…

  • Collagenase Type II from Clostridium histolyticum

    MP Biomedicals

    Collagenases degrade native helical collagen fibrils. Plays an important role in connective tissue metabolism Produced by specific cells involved in repairs and remodeling processes Type II enzyme that contains greater clostripain activity Collagenase is used for collagen…

  • 5-Bromo-2'-Deoxyuridine

    MP Biomedicals

    5-Bromo-2’-deoxyuridine is a thymidine analog and useful for the study of DNA synthesis where it is incorporated into DNA in place of thymidine. Measure DNA synthesis Label dividing cells Study cell signaling and processes that induce cell proliferation Used as a mutagen in…

  • Diastase from Malt

    MP Biomedicals

    1X N.F. Stable, 60 mesh powder. 1 gram will digest 50 gram starch in 30 minutes.

  • Cholesterol Esterase

    MP Biomedicals

    Cholesterol Esterase is useful for enzymatic determination of total cholesterol when coupled with cholesterol oxidase in clinical analysis. Stored intracellularly as cholesterol esters Reversible enzyme Hydrolyzes and synthesizes fatty acid esters of cholesterol and other sterols …

  • Spermidine, Trihydrochloride

    MP Biomedicals

    Spermidine is a biogenic polyamine formed from putrescine. Essential in both normal and neoplastic tissue growth Plays an important role in the regulation of cellular proliferation and differentiation Forms stable compounts with nucleic acids Inhibits neuronal nitric oxide synthase…

  • a-Chymotripsin from Bovine Pancreas

    MP Biomedicals

    A serine protease that hydrolyzes peptide bonds with aromatic or large hydrophobic side chains (Tyr, Trp, Phe, Met, Leu) on the carboxyl end of the bond. Produced from 3x Crystallized chymotrypsinogen Used to treat pancreatic insufficiency Used in traumatology Chymotrypsin…

  • Acetyl Coenzyme A Trilithium Salt Trihydrate

    MP Biomedicals

    Acetyl-CoA is produced via beta-oxidation of fatty acids, via the metabolism of carbohydrates - glucose 6-phosphate to pyruvate to acetyl-CoA and via the catabolism of amino acids. Acetyl-CoA has a number of metabolic opportunities. It is metabolized in the tricarboxylic acid cycle to produce…

  • Phenylmethylsulfonyl Fluoride

    MP Biomedicals

    Phenylmethylsulfonyl fluoride is an irreversible inhibitor of serine proteases - inhibits trypsin, chymotrypsin and protease. Inhibits mammalian acetyl cholinesterase, but not those from fish sources. Administration of PMSF produces analgesia unrelated to its anticholinesterase effect, and…

  • Pepstatin A

    MP Biomedicals

    Pepstatin A is a reversible inhibitor of aspartic proteases, Inhibitor for pepsin, renin, cathepsin D, cathepsin G, and other acid proteases. It does not inhibit thiol proteases, neutral proteases or serine proteases. Pepstatin forms a 1:1 complex with acid proteases (carboxyl proteases). …

  • 4-(2-Aminoethyl)-Benzenesulfonyl Fluoride Hydrochloride

    MP Biomedicals

    AEBSF hydrochloride is a covalent binding serine protease inhibitor, belongs to the family of irreversible sulfonyl fluoride inhibitors that block trypsin and chymotrypsin-type enzymes. Similar in structure to the commonly used inhibitor PMSF, AEBSF offers better solubility in water, lower…

  • Leupeptin Hemisulfate

    MP Biomedicals

    Leupeptin is a modified tripeptide reversible protease inhibitor of trypsin-like proteases and some cysteine proteases including endoproteinase Lys-C, kallikrein, papain, thrombin, cathepsin B, cathepsins H and L, trypsin, calpain, trypsin8 and plasmin. Effective concentration is typically 10-100…

  • E-64 from Synthetic

    MP Biomedicals

    E-64 is an inhibitor for thiol protease, papain, actinidin, ananain, bromelain, calpain and cathepsin B. It is an irreversible cysteine protease inhibitor that has no action on cysteine residues in other plants and does not react with low molecular weight thiols such as 2-mercaptoethanol. Specific…

  • ß-Glucosidase from Sweet Almonds

    MP Biomedicals

    β-Glucosidase is a glucosidase enzyme. It is an exocellulase with specificity for a variety of β-D-glycoside substrates. β-Glucosidase is used in the synthesis of glucosides and fucosides with various potential applications in pharmaceutical, cosmetic and detergent industries,…

  • Deoxyribonuclease I from Bovine Pancreas

    MP Biomedicals

    Deoxyribonuclease from beef pancreas, DNase I, was first crystallized by Kunitz. It is an endonuclease which splits phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide yielding 5'-phosphate terminated polynucleotides with a free hydroxyl group on position 3'. The…

  • Creatine Amidohydrolase from Pseudomonas sp.

    MP Biomedicals

    This enzyme is useful for enzymatic determination of creatinine when coupled with creatine amidinohydrolase, sarcosine dehydrogenase or sarcosine oxidase and formaldehyde dehydrogenase in clinical analysis. Creatininase from Pseudomonas sp. is a homohexameric enzyme with a molecular mass of 28.4…

  • Pectolyase from Aspergillus japonicus

    MP Biomedicals

    Pectolyase contains two types of pectinase, endopolygalacturonase (E.C.3.2.1.15), endo-pectin lyase (E.C.4.2.2.3) and a maceration stimulating factor. Pectolyase is used in plant protoplast preparation to digest cell wall prior to organelle isolation. Pectolyase catalyzes the eliminative…

  • Naproxen

    MP Biomedicals

    Pharmacological agent that reportedly may show activity through ability to inhibit prostaglandin biosynthesis. Non-selective cyclooxygenase (COX-1 and COX-2) inhibitor. Naproxen has been demonstrated to block Aβ fibril growth and form a complex with copper (II).

  • Pepsin from Porcine Stomach Mucosa

    MP Biomedicals

    Pepsin, an acid protease, contains a proteolytic enzyme. Pepsin contains the "cathepsin" component which has milk curdling activity. It has a broad range of substrate activity and demonstrates an esterase acitivity. It generally attacks peptide bonds. Pepsin is a peptidase used to…

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