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Enzymes & Inhibitors, MP Biomedicals

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MP Biomedicals Enzymes & Inhibitors

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  • Diastase from Malt

    MP Biomedicals

    1X N.F. Stable, 60 mesh powder. 1 gram will digest 50 gram starch in 30 minutes.

  • Lysozyme from Chicken Eggwhite

    MP Biomedicals

    Lysozyme (muramidase) hydrolyzes preferentially the β-1,4 glucosidic linkages between N-acetylmuramic acid and N-acetylglucosamine which occur in the mucopeptide cell wall structure of certain microorganisms, such as Micrococcus lysodeikticus. Extracts group specific antigens …

  • Catalase from Beef Liver

    MP Biomedicals

    Catalase is an oxidoreductase that catalyzes the conversion of hydrogen peroxide to water and oxygen. Activates the decomposition of hydrogen peroxide Natural antioxidant Used to study roles of reactive oxygen species in gene expression and apoptosis Hydrogen peroxide is a harmful…

  • Alcohol Oxidase from Pichea Pastoris

    MP Biomedicals

    ≥10 u/mg Protein, Reddish Brown Frozen Liquid Alcohol oxidase has been detected in several strains of yeast,such as Candida, Pichia, and Hansenula,that utilize methanol as a sole carbon and energy source. Some of these enzymes have been isolated and partially characterized. Alcohol oxidase…

  • Cholesterol Esterase

    MP Biomedicals

    Cholesterol Esterase is useful for enzymatic determination of total cholesterol when coupled with cholesterol oxidase in clinical analysis. Stored intracellularly as cholesterol esters Reversible enzyme Hydrolyzes and synthesizes fatty acid esters of cholesterol and other sterols …

  • Protease Inhibitor Cocktail Kit

    MP Biomedicals

    Protease Inhibitor Cocktail Kit is a broad spectrum protease inhibitor cocktail which covers both endopeptidases and exopeptidases, non-specific and specific. The cocktail consists of four major protease inhibitors: AEBSF, Sodium EDTA, Leupeptin and Pepstatin A. Protease Inhibitor Cocktail Kit…

  • Pepsin from Porcine

    MP Biomedicals

    Pepsin, an acid protease, contains a proteolytic enzyme. Pepsin contains the "cathepsin" component which has milk curdling activity. It has a broad range of substrate activity and demonstrates an esterase acitivity. It generally attacks peptide bonds. Pepsin is a peptidase used to…

  • Acetoacetyl Coenzyme A Trisodium Salt Tetrahydrate

    MP Biomedicals

    Acetoacetyl coenzyme A (Acetoacetyl-CoA) may be used as a substrate for a number of enzymes including; acetoacetyl-CoA thiolase (EC 2.3.1) which produces acetyl-CoA in reverse condensation reaction and (3-Hydroxy-3-methylglutaryl coenzyme A (CoA) synthase (HMGCS)) which produces…

  • Collagenase Type II from Clostridium histolyticum

    MP Biomedicals

    Collagenases degrade native helical collagen fibrils. Plays an important role in connective tissue metabolism Produced by specific cells involved in repairs and remodeling processes Type II enzyme that contains greater clostripain activity Collagenase is used for collagen…

  • 5-Bromo-2'-Deoxyuridine

    MP Biomedicals

    5-Bromo-2’-deoxyuridine is a thymidine analog and useful for the study of DNA synthesis where it is incorporated into DNA in place of thymidine. Measure DNA synthesis Label dividing cells Study cell signaling and processes that induce cell proliferation Used as a mutagen in…

  • Spermidine, Trihydrochloride

    MP Biomedicals

    Spermidine is a biogenic polyamine formed from putrescine. Essential in both normal and neoplastic tissue growth Plays an important role in the regulation of cellular proliferation and differentiation Forms stable compounts with nucleic acids Inhibits neuronal nitric oxide synthase…

  • a-Chymotripsin from Bovine Pancreas

    MP Biomedicals

    A serine protease that hydrolyzes peptide bonds with aromatic or large hydrophobic side chains (Tyr, Trp, Phe, Met, Leu) on the carboxyl end of the bond. Produced from 3x Crystallized chymotrypsinogen Used to treat pancreatic insufficiency Used in traumatology Chymotrypsin…

  • Acetyl Coenzyme A Trilithium Salt Trihydrate

    MP Biomedicals

    Acetyl-CoA is produced via beta-oxidation of fatty acids, via the metabolism of carbohydrates - glucose 6-phosphate to pyruvate to acetyl-CoA and via the catabolism of amino acids. Acetyl-CoA has a number of metabolic opportunities. It is metabolized in the tricarboxylic acid cycle to produce…

  • Phenylmethylsulfonyl Fluoride

    MP Biomedicals

    Phenylmethylsulfonyl fluoride is an irreversible inhibitor of serine proteases - inhibits trypsin, chymotrypsin and protease. Inhibits mammalian acetyl cholinesterase, but not those from fish sources. Administration of PMSF produces analgesia unrelated to its anticholinesterase effect, and…

  • Pepstatin A

    MP Biomedicals

    Pepstatin A is a reversible inhibitor of aspartic proteases, Inhibitor for pepsin, renin, cathepsin D, cathepsin G, and other acid proteases. It does not inhibit thiol proteases, neutral proteases or serine proteases. Pepstatin forms a 1:1 complex with acid proteases (carboxyl proteases). …

  • 4-(2-Aminoethyl)-Benzenesulfonyl Fluoride Hydrochloride

    MP Biomedicals

    AEBSF hydrochloride is a covalent binding serine protease inhibitor, belongs to the family of irreversible sulfonyl fluoride inhibitors that block trypsin and chymotrypsin-type enzymes. Similar in structure to the commonly used inhibitor PMSF, AEBSF offers better solubility in water, lower…

  • Leupeptin Hemisulfate

    MP Biomedicals

    Leupeptin is a modified tripeptide reversible protease inhibitor of trypsin-like proteases and some cysteine proteases including endoproteinase Lys-C, kallikrein, papain, thrombin, cathepsin B, cathepsins H and L, trypsin, calpain, trypsin8 and plasmin. Effective concentration is typically 10-100…

  • E-64 from Synthetic

    MP Biomedicals

    E-64 is an inhibitor for thiol protease, papain, actinidin, ananain, bromelain, calpain and cathepsin B. It is an irreversible cysteine protease inhibitor that has no action on cysteine residues in other plants and does not react with low molecular weight thiols such as 2-mercaptoethanol. Specific…

  • Diethyl Pyrocarbonate

    MP Biomedicals

    Clear, Colorless Liquid Synonyms: Diethyl Oxydiformate, Dicarbonic Acid Diethyl Ester, DEPC, Ethoxyformic acid anhydride, Diethyl dicarbonate CAS Number: 1609-47-8 Molecular Formula: C6H10O5 Molecular Weight: 162.1 Beilstein…

  • Creatine Amidohydrolase from Pseudomonas sp.

    MP Biomedicals

    This enzyme is useful for enzymatic determination of creatinine when coupled with creatine amidinohydrolase, sarcosine dehydrogenase or sarcosine oxidase and formaldehyde dehydrogenase in clinical analysis. Creatininase from Pseudomonas sp. is a homohexameric enzyme with a molecular mass of 28.4…

  • Hydroxylamine Hydrochloride

    MP Biomedicals

    MAO inhibitor; inhibits platelet aggregation.

  • Neuraminidase from Arthrobacter ureafaciens

    MP Biomedicals

    Neuraminidase enzymes are glycoside hydrolase enzymes. Neuraminidases are used to cleave N-acetyl neuraminic acid (sialic acid) from a variety of glycoproteins. One unit will liberate 1.0 µmole of N-acetyl-neuraminic acid (NANA) per minute at pH 5.0 at 37°C, using either one…

  • Phosphodiesterase I from Crotalus adamanteus

    MP Biomedicals

    Phosphodiesterase I successively hydrolyzes 5'-mononucleotides from 3'-hydroxy-terminated ribo- and deoxyribo-oligonucleotides. ADP-ribosylated proteins are cleaved at the pyrophosphate linkages by venom phosphodiesterases to yield phosphoribosyl-AMP. Enzyme that is used to break…

  • Hyaluronidase from Bovine Testes

    MP Biomedicals

    Hyaluronidase is a glycoprotein containing 5% mannose and 2.17% glucosamine, it catalyzes the random hydrolysis of 1,4-linkages between 2-acetamido- 2-deoxy- b-D-glucose and D-glucose residues in hyaluronate. Hyaluronidase from bovine testes is a tetramer consisting of 4 equal subunits with a…

  • Thrombin from Bovine

    MP Biomedicals

    α-Thrombin is a trypsin-like serine protease involved in a multitude of processes in the human body. Thrombin generation is the result of limited proteolysis of the vitamin K-dependent zymogen prothrombin. Thrombin is the last enzyme in the clotting cascade functioning to cleave fibrinogen to…

  • a-Chymotrypsin 1X Crystallized from Bovine Pancreas

    MP Biomedicals

    α-Chymotrypsin preferentially catalyzes the hydrolysis of peptide bonds involving L-isomers of tyrosine, phenylalanine, and tryptophan. It also readily acts upon amides and esters of susceptible amino acids. In addition to bonds involving aromatic amino acids, chymotrypsin catalyzes at a high…

  • Amylase, Fungal from Aspergillus oryzae

    MP Biomedicals

    The number of grams of soluble starch dextrinized in the presence of excess B-amylase per hour at 40°C, pH 5.0.

  • Iodoacetamide

    MP Biomedicals

    Iodoacetamide is a thiol reagent; alkylating reagent for cysteine and histidine residues in proteins. In the alkylation reaction, it reacts with histidine (such as in RNase), methionine and sulfhydryl groups of many proteins. Iodoacetamide can react with low molecular weight thiol compounds such as…

  • Catalase from Bovine Liver

    MP Biomedicals

    Catalase from bovine liver is a homotetrameric enzyme that is primarily located in peroxisomes. Activates the decomposition of hydrogen peroxide Natural antioxidant used to study roles of reactive oxygen species Catalyzes the decomposition of hydrogen peroxide into water and oxygen …

  • Carbonic Anhydrase from Bovine Erythrocytes

    MP Biomedicals

    Carbonic anhydrase from bovine erythrocytes (BCA) has been used to study the effect of removal of enzyme-bound metal ion, Zn2+, on aggregation behavior of the enzyme. Removal of metal ion by a chelator such as EDTA enhances the propensity of the enzyme to adopt the molten-globule state. This state…

  • Neuraminidase from Bacterial

    MP Biomedicals

    A highly purified, neuraminidase of non-pathogenic streptococci. Prepared from the culture filtrate by ammonium sulfate precipitation and ion-exchange chromatography. One units causes the hydrolysis of one µmole of sialyllactose per minute @ pH 6.5, 37°C.

  • Catalase from Aspergillus niger

    MP Biomedicals

    Catalase, Fungal suspension from from Aspergillus niger is long-acting, extremely stable form of catalase that is active over a wide pH range. Composed of four protein subunits Each subunit contains a heme group bound to its active site Catalase is used for the removal of peroxides,…

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