LKT Labs

Biologically Active Small Molecules, LKT Labs

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LKT Labs Biologically Active Small Molecules

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  • Biapenem

    LKT Labs

    Biapenem is a carbapenem ß-lactam antibiotic. Like other carbapenems, biapenem binds penicillin-binding proteins to inhibit bacterial cell wall synthesis. Biapenem exhibits broad spectrum antibacterial activity and is clinically used to treat respiratory and urinary tract infections. Biapenem…

  • Astilbin

    LKT Labs

    Astilbin is a flavonoid found in several plants, including species of Engelhardia and Smilax. Astilbin displays anticancer, antioxidative, anti-inflammatory, and immunosuppressive activities. In vitro, astilbin inhibits expression of IL-1ß, IL-6, IL-10, MCP-1, and TNF-a, as well as activity of…

  • Allicin, aqueous solution

    LKT Labs

    Allicin is an thiocyanate found in garlic; it exhibits a wide variety of properties, including anticancer, antioxidative, cardioprotective, antihypertensive, anti-arrhythmic, anti-parasitic, and anti-diabetic activities. In vitro, allicin binds cellular nucleic acids, primarily nitrogenous bases…

  • Aristolochic Acid B

    LKT Labs

    Aristolochic acid B is a carcinogenic compound found in Aristolochia and Radix that has commonly been used in traditional Chinese medicine.

  • Aflatoxin B2

    LKT Labs

    Aflatoxins are mycotoxins found in foods and livestock feeds that were initially produced by species of Aspergillus. Aflatoxin B2 is cytotoxic; it inhibits DNA synthesis and induces cell cycle arrest.

  • Antimycin A

    LKT Labs

    Antimycin A was initially produced by Streptomyces. Antimycin A binds cytochrome c reductase, inhibiting electron transport chain activity, oxidative phosphorylation, and ATP synthesis. Antimycin A is used in research models to study mitochondrial respiration and superoxide production. Grade: ≥98%

  • Aflatoxin M1

    LKT Labs

    Aflatoxins are mycotoxins found in foods and livestock feeds that were initially produced by species of Aspergillus. Aflatoxin M1 is the hydroxylated metabolite of aflatoxin B1; it inhibits DNA synthesis and induces cell cycle arrest.

  • 7-Aminoactinomycin D

    LKT Labs

    7-Aminoactinomycin D (7AAD) binds DNA sequences and is used in cellular assays to measure apoptosis and phagocytosis.

  • Aztreonam

    LKT Labs

    Aztreonam is a synthetic ß-lactam antibiotic that displays antibacterial activity against gram negative bacteria. Like similar compounds, aztreonam inhibits penicillin binding proteins.

  • Aflatoxin M2

    LKT Labs

    Aflatoxins are mycotoxins found in foods and livestock feeds that were initially produced by species of Aspergillus. Aflatoxin M2 is the hydroxylated metabolite of aflatoxin B2; it inhibits DNA synthesis and induces cell cycle arrest.

  • Alamethicin

    LKT Labs

    Alamethicin is a peptabiol peptide initially produced by species of Trichoderma. Alamethicin is an antimicrobial peptide (AMP) that disturbs the lipid layer of the cell membrane, aggregating and forming pores and causing cell lysis. Grade: ≥95%

  • Butylated Hydroxytoluene

    LKT Labs

    Butylated hydroxytoluene (BHT) is commonly used as a food and cosmetics additive; it exhibits antioxidative and anti-inflammatory activities. BHT may also display neuroprotective benefit, decreasing ethanol-induced brain damage and neurodegeneration and suppressing activation of NF-?B activation…

  • Chlorogenic Acid (from Eucommia)

    LKT Labs

    Chlorogenic acid is a polyphenol derivative of caffeic acid found in Eucommia bark that exhibits a wide variety of beneficial properties, including antibacterial, antioxidative, anti-inflammatory, hepatoprotective, neuroprotective, anti-allergic, anticancer chemotherapeutic, and chemopreventive…

  • Acarbose

    LKT Labs

    a-Glucosidase inhibitor that decreases digestion of complex carbohydrates and prevents glucose absorption. It improves insulin sensitivity and decreases postprandial hyperglycemia.

  • Benzo[a]pyrene

    LKT Labs

    Benzo[a]pyrene is a polycyclic aromatic hydrocarbon (PAH) originally found in coal tar, cigarette smoke, and wood smoke. Metabolites of this compound bind DNA and induce mutations. Benzo[a]pyrene is highly carcinogenic and is used in research models to induce carcinogenesis and tumor formation.…

  • Caffeic Acid

    LKT Labs

    Caffeic acid is a hydroxycinnamic acid found in coffee, argan oil, Eucaplyptus, Salvinia, and Phellinus; it exhibits antioxidative, anti-diabetic, antibiotic, anti-inflammatory, anti-metastatic, and anticancer activities. Caffeic acid inhibits activity of a-amylase and a-glucosidase. This compound…

  • Aspartame

    LKT Labs

    Aspartame is a dipeptide ester that is used as an artificial sweetener in commercial food production. Aspartame exhibits antibacterial efficacy against Porphyromonas, a periodontal pathogen. In vivo, aspartame also displays antinociceptive activity, increasing latency times in tail flick and paw…

  • 1,4-Benzoquinone

    LKT Labs

    1,4-Benzoquinone is a precursor used in the synthesis of hydroquinone and is also used as a hydrogen acceptor and oxidant. 1,4-Benzoquinone exhibits anti-inflammatory and antibiotic activities. 1,4-Benzoquinone inhibits 5-lipoxygenase and prevents leukotriene synthesis. Additionally, this compound…

  • Azithromycin Dihydrate

    LKT Labs

    Azithromycin is an azalide macrolide antibiotic derived from erythromycin. Azithromycin binds the bacterial 50S ribosomal subunit, inhibiting protein translation. Azithromycin displays antibacterial, anti-fibrotic, and anti-inflammatory activities. In epithelial cells, azithromycin inhibits the…

  • Cisplatin

    LKT Labs

    Cisplatin is a platinum-based cross-linking agent that exhibits anticancer chemotherapeutic activity. Cisplatin induces crosslinks between guanine bases on DNA; it is clinically used to treat various forms of cancer. In lung cancer cells, cisplatin decreases phosphorylation of PI3K, Akt, and FOXO3a…

  • L-Arginine

    LKT Labs

    L-Arginine is an endogenous amino acid also found in meat, dairy, grains, and legumes. L-Arginine exhibits vasodilatory and antihypertensive activities, as it is a precursor to the formation of NO. L-Arginine decreases systolic and diastolic blood pressure, improving cardiovascular and endothelial…

  • Cefotaxime Acid

    LKT Labs

    Cefotaxime is a third generation β-lactam cephalosporin antibiotic. Cefotaxime exhibits antibacterial efficacy against gram positive and gram negative bacteria, inhibiting penicillin binding proteins to prevent peptidoglycan synthesis and bacterial cell wall formation. Cefotaxime is also…

  • Capsaicin, natural

    LKT Labs

    Capsaicin is an agonist of transient receptor potential vanilloid (TRPV) channels that was originally found in peppers of the Capsicum genus. Capsaicin exhibits analgesic, anti-inflammatory, anti-obesity, and anticancer chemotherapeutic activity. Capsaicin also displays bronchoconstrictive activity…

  • Bleomycin Sulfate

    LKT Labs

    This product is a mixture of bleomycin sulfate salts; bleomycin A2 is pictured. Bleomycin is an anticancer chemotherapeutic that binds DNA and induces DNA cleavage and strand breaks; it is highly toxic. Bleomycin A5 is clinically used to treat lymphomas, squamous cell carcinomas, and testicular…

  • N-Acetyl-L-Cysteine

    LKT Labs

    N-Acetyl-L-cysteine exhibits antioxidative, mucolytic, anti-inflammatory, antiviral, antipsychotic, and neuromodulatory activities. N-Acetyl-L-cysteine has clinically been used to treat acetaminophen overdose; it is occasionally commercially sold as a supplement. N-Acetyl-L-cysteine acts as a…

  • Abamectin

    LKT Labs

    F0F1-ATPase and adenine nucleotide translocator inhibitor and GABA receptor antagonist. It prevents mitochondrial respiration and decreases sperm count and motility. Grade: ≥70%

  • L-(+)-Ascorbic Acid

    LKT Labs

    L-Ascorbic acid is a vitamin C compound that can be found in many food and plant sources. L-Ascorbic acid exhibits antioxidative benefit and reducing activity; in vitro, it can act as a prolyl hydroxylase cofactor. Grade; ≥98%

  • Berberine Chloride

    LKT Labs

    Berberine is an isoquinoline alkaloid found in a variety of plants, including barberry, goldenseal, Oregon grape, California poppy, and the Amur cork tree. Berberine fluoresces under ultraviolet light and is often used to stain heparin in mast cells. Berberine displays many beneficial effects,…

  • (+)-Catechin

    LKT Labs

    Catechin is a flavanol originally found in Camilla and other plant sources; it exhibits antioxidative, anti-aging, anti-atherosclerotic, anti-ulcerative, neuroprotective, neuromodulatory, anticancer chemotherapeutic, and chemopreventive activities. Catechin increases life span in Caenorhabditis…

  • Aflatoxin B1

    LKT Labs

    Aflatoxins are mycotoxins found in foods and livestock feeds that were initially produced by species of Aspergillus. Aflatoxin B1 is the most cytotoxic of all aflatoxins; it inhibits DNA synthesis and induces cell cycle arrest.

  • Aminopterin

    LKT Labs

    Aminopterin is a folic acid analog and derivative of pterin; it is very similar to methotrexate in structure. Aminopterin exhibits anticancer chemotherapeutic and immunosuppressive activities. Like other folic acid analogs, aminopterin inhibits dihydrofolate reductase, depleting nucleotide pools…

  • Biopterin

    LKT Labs

    Biopterin is an endogenous pterin coenzyme that acts as a cofactor for amino acid hydroxylases that produce neurotransmitters and bind NOS to stimulate NO release.

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