Biologically Active Small Molecules, 69-09-0

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69-09-0 Biologically Active Small Molecules

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  • Chlorpromazine is a phenothiazine that exhibits antipsychotic, antidepressant, anxiolytic, neuroprotective, and anticancer chemotherapeutic activities. Chlorpromazine inhibits D1/2/3/4 receptors, 5-HT1/2 receptors, a1/2-adrenergic receptors, and M1/2 muscarinic acetylcholine receptors (mAChRs).…

  • Chlorophyllin is a semi-synthetic derivative of chlorophyll that is commercially used as a food additive and coloring agent. Chlorophyllin exhibits anti-angiogenic, anticancer chemotherapeutic, and chemopreventive activities. Chlorophyllin can act as a photosensitizer, inducing apoptosis and…

  • A phenothiazine classified as an antipsychotic compound; antagonizes dopamine and serotonin receptors (Kis = 0.66, 0.84, 1.2, and 1.8 nM for D2, D3, D4, and 5-HT2A, respectively); also antagonizes histamine, α1- and α2-adrenergic, and muscarinic acetylcholine receptors.

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