Aminonucleoside antiobiotic allows selection of cells expressing the pac gene. Inhibits growth of gram positive bacteria and various animal and insect cells.

MW: 544.43 C₂₂H₂₉N₇O₅ · 2HCl Mode of action and Anti-microbial spectrum: Puromycin is a protein synthesis inhibitor that causes premature chain termination by acting as an analog of the 3′-terminal end of aminoacyl-tRNA. It prevents…

Puromycin is an antibiotic of unique structure and biological activity. It is produced by fermentation using Streptomyces albo-niger. There are four aspects of puromycin's biological activity that are 1) antitumor effect; 2) nephrotoxic action; 3) inhibition of purine and/or protein synthesis…