- Promotes cell adhesion and differentiation of a variety of cell types and proliferation of PC12 cells
Collagen IV is a ubiquitous component of basement membranes, the sheet-like matrix found in close proximity to epithelial, muscle, and nerve cells. Collagen IV plays a role in the regulation of cell growth, differentiation, and adhesion, as well as tissue formation.
BD BioCoat™ Collagen IV Cellware are tissue culture vessels with a uniform application of mouse collagen type IV. This cellware is manufactured in a highly controlled environment and rigorously tested to assure product consistency and performance.
Applications include:
- Promotion of cell attachment and spreading
- Cell differentiation and neurite outgrowth
- Increased proliferation of PC12 cells
- Studies of effects of Collagen IV on cell behavior
- Cell adhesion assays
- Serum-free or reduced serum culture
Quality Control:
Tested for ability to promote attachment and spreading of PC12 rat pheochromocytoma cells or to initiate differentiation (neurite outgrowth) of NG-108 rat glioma/mouse neuroblastoma cells. Tested and found- negative for bacteria and fungi. Collagen IV purity >90% by SDS-PAGE
Storage and Stability:
Stable for at least three months at 2-8°C. Do not freeze.