Signal Transduction

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  • Image of Ag-825

    Ag-825

    98%, MW=397.5, Storage: RT 5-[(Benzthiazol-2-yl)thiomethyl]-4-hydroxy-3-methoxybenzylidenecyanoacetamide. A selective HER1-2 (HER2-Neu) 1 tyrosine kinase inhibitor 2 . 1. A. Levitzki et al., "Science" 1995, 267: 1782 2. H. Daub et al., "Nature" 1996, 379: 559
  • Image of Antibiotic A-23187, 4-bromo

    Antibiotic A-23187, 4-bromo

    Item #: C002A25
    98%, MW=602.5 [76455-82-8] Storage: -20°C A highly selective calcium ionophore which is a useful tool for increasing intracellular Ca 2+ concentration. A nonfluorescent analog of A-23187 (Thomas No. C002A24) and therefore useful in the presence of fluorescent probes 1 . 1. C.M. Deber and L.C....
  • Image of Antibiotic A-23187, 10 mg

    Antibiotic A-23187, 10 mg

    Item #: C002A24
    99%, MW=523.6 [52665-69-7] Storage: -20°C A highly selective calcium ionophore 1 . Useful tool for increasing intracellular Ca 2+ concentration. 1. K. Geitzen et al., "Biochem. J." 1982, 207 541
  • Image of Anti-Cyclophilin A, 100 ug

    Anti-Cyclophilin A, 100 ug

    Item #: C002A89
    Storage: -80°C. Upon initial thawing, aliquot into smaller portions. Avoid freeze/thaw cycles. Rabbit polyclonal antibody Immunogen: Recombinant human cyclophilin A conjugated to KLH Supplied as serum Recognizes human, rat, and mouse cyclophilin A 18 kDa protein. The optimal antibody...
  • Image of Anti-Histone Deacetylase 1, 100 ug

    Anti-Histone Deacetylase 1, 100 ug

    Item #: C002A90
    Rabbit polyclonal antibody Immunogen: C-terminal human HDAC1 (467-482) Supplied as epitope affinity purified IgG with 1 mg/ml BSA and 0.05% sodium azide in PBS. Recognizes human HDAC1 (approximately 62 kDa). Applications: Western Blotting 1/2000, Immunoprecipitation.
  • Image of Anti-Histone Deacetylase 2, 100 ug

    Anti-Histone Deacetylase 2, 100 ug

    Item #: C002A91
    Rabbit polyclonal antibody Immunogen: C-terminal human HDAC2 (475-488) Supplied as epitope affinity purified IgG with 1 mg/ml BSA and 0.05% sodium azide in PBS. Recognizes human HDAC2 (approximately 55 kDa). Applications: Western Blot 1/2000, Immunoprecipitation.
  • Image of Anti-Histone Deacetylase 3, 100 ug

    Anti-Histone Deacetylase 3, 100 ug

    Item #: C002A92
    Rabbit polyclonal antibody Immunogen: C-terminal human HDAC3 (415-428) Supplied as epitope affinity purified IgG with 1 mg/ml BSA and 0.05% sodium azide in PBS. Recognizes human HDAC3 (approximately 48 kDa). Applications: Western Blot 1/2000, Immunopreciptation.
  • Image of Anti-Phosphotyrosine, 100 ug

    Anti-Phosphotyrosine, 100 ug

    Item #: C002A83
    Rabbit polyclonal antibody Immunogen: Phosphotyrosine conjugated to KLH Supplied as IgG, affinity purified against immobilized phosphotyrosine. Applications: WB 1-5 µg/ml, ELISA
  • Image of Bapta-Am

    Bapta-Am

    Item #: C002A27
    >90%, MW=764.7 [139890-68-9] Storage: -20°C 1,2-bis-(o-Aminophenoxy)-ethane-N,N,N',N'-tetraacetic acid, tetraacetoxymethyl ester. BAPTA is a Ca2+ chelator 1,2 with 105-fold greater affinity for Ca 2+ than for Mg 2+ 1,2 . BAPTA-AM is a cell permeable derivative which is widely used as an...
  • Image of Bapta, Free Acid

    Bapta, Free Acid

    97%, MW=476.4 [85233-19-8] Storage: -20°C 1,2-bis-(o-Aminophenoxy)-ethane-N,N,N',N'-tetraacetic acid. BAPTA is a Ca 2+ chelator with 105-fold greater affinity for Ca 2+ than for Mg 2+ 1,2 . BAPTA, free acid is not cell permeable and therefore is useful as an extracellular calcium sponge 3-5 ....
  • Image of Biomol Green Reagent

    Biomol Green Reagent

    The BIOMOL GREEN™ Reagent is a convenient, 1-step reagent for measuring the free phosphate released during enzymatic phosphatase assays. It is a modification of the classic Malachite green reagent 1,2 and it offers the following advantages: Non-Radioactive Convenient one-step reagent: No...
  • Image of Calcineurin Colorimetric Drug Discovery Kit - A

    Calcineurin Colorimetric Drug Discovery Kit - A

    Item #: C002A21
    Non-Radioactive Convenient 1-Step Detection: No mixing Microtiter Plate Format: For high-throughput This colorimetric assay kit is useful for measuring calcineurin (PP2B) phosphatase activity of purified enzyme and for screening inhibitors. The assay is performed in a convenient 96-well plate...
  • Image of Caspase-9, Caspase-9 Full Length

    Caspase-9, Caspase-9 Full Length

    >95% by SDS-PAGE, MW=20 + 12 kDa Storage: -80°C Caspase-9 is the initiator caspase of the mitochondrial/Apaf-1 apoptosis induction pathway 3-6 . This active caspase-9 (ICE-LAP-6; Mch6) is made from a human cDNA, expressed in E. coli. cDNA encodes residues identical to Ile-131 to Ser-416...
  • Image of Caspase-3 Cellular Assay Kit PLUS - A Quantizyme

    Caspase-3 Cellular Assay Kit PLUS - A Quantizyme

    Item #: C002A20
    This kit is a complete assay system for measuring caspase-3 and caspase-3-like activity (DEVDase) in cellular extracts. It includes both colorimetric and fluorogenic substrates. It is performed in a convenient 96-well format with all reagents necessary for preparing cell extracts, measuring caspase...
  • Image of Caspase-1, 5000 U

    Caspase-1, 5000 U

    Item #: C002B11
    >95% by SDS-PAGE, MW=20 + 10 kDa Human Recombinant Storage: -80°C Highly active caspase-1 (Interleukin-1 converting enzyme; ICE) from human cDNA, expressed in E. coli. Caspase-1 is thought to be primarily involved in regulation of inflammation, specifically the proteolytic processing of...
  • Image of Caspase-10, 5000 U

    Caspase-10, 5000 U

    Item #: C002B17
    >95% by SDS-PAGE, MW=17 + 12 kDa Storage: -80°C Caspase-10 is an initiator caspase, highly homologous to caspase-8, a relationship that extends to the death effector domains (DEDs) of their proforms 1,2,3 . Caspase-10 was reported to activate early in TRAIL-induced apoptosis and was found in...
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