Synonyms: RFP; RNF76; TRIM27
Storage: -20C
UNSPSC Code: 12352203
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Application: Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, IP: 1:100-1:500, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Biochem/physiol Actions: This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein. [provided by RefSeq]
Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 218 of TRIM27 according to NP_006501
Physical form: 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
RIDADR: NONH for all modes of transport
WGK Germany: 1